Molecular Cell

Rewiring cell metabolism slows colorectal cancer growth

Cancer is an unwanted experiment in progress. As the disease advances, tumor cells accumulate mutations, eventually arriving at ones that give them the insidious power to grow uncontrollably and spread. Distinguishing ...

Oct 30, 2014
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Scientists link excess sugar to cancer

Sugars are needed to provide us with energy and in moderate amounts contribute to our well-being. Sustained high levels of sugars, as is found in diabetics, damages our cells and now is shown that can also ...

Feb 01, 2013
popularity 4.7 / 5 (19) | comments 12 | with audio podcast

Applying proteomics to Parkinson's

(Medical Xpress)—Scientists studying two genes that are mutated in an early-onset form of Parkinson's disease have deciphered how normal versions of these genes collaborate to help rid cells of damaged ...

Oct 03, 2014
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Uncovering the genome's regulatory code

Since the sequencing of the human genome in 2001, all our genes – around 20,000 in total – have been identified. But much is still unknown – for instance where and when each is active. Next to each ...

Sep 10, 2012
popularity 5 / 5 (1) | comments 1 | with audio podcast

Super enhancers in the inflamed endothelium

Normally, the lining of blood vessels, or endothelium, when at rest, acts like Teflon, ignoring the many cells and other factors rushing by in the bloodstream. In response to inflammatory signals, as well as other stimuli, ...

Sep 25, 2014
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Research reveals mechanism behind cell protein remodeling

The remodeling of a kitchen or bathroom changes the appearance of the room and improves its functionality. As investigators at Rutgers Cancer Institute of New Jersey and Rutgers and Princeton Universities have demonstrated, ...

Sep 03, 2014
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New control target for cancer metabolism: Acetylation

(Medical Xpress)—Cancer cells are not interested in sustainability. They gobble up sugar inefficiently, brushing aside their mitochondria, the efficient miniature power plants that supply energy to healthy ...

Feb 06, 2014
popularity 5 / 5 (4) | comments 0 | with audio podcast