Molecular Cell

Protein preps cells to survive stress of cancer growth and chemotherapy

Scientists have uncovered a survival mechanism that occurs in breast cells that have just turned premalignant-cells on the cusp between normalcy and cancers-which may lead to new methods of stopping tumors.

Cancer created May 23, 2013 | popularity not rated yet | comments 0 | with audio podcast

Research identifies a way to make cancer cells more responsive to chemotherapy

Breast cancer characterized as "triple negative" carries a poor prognosis, with limited treatment options. In some cases, chemotherapy doesn't kill the cancer cells the way it's supposed to. New research from Western University ...

Cancer created May 23, 2013 | popularity 5 / 5 (3) | comments 0

Faulty energy production in brain cells leads to disorders ranging from Parkinson's to intellectual disability

Neuroscientist Patrik Verstreken of VIB (Flanders Institute for Biotechnology) and KU Leuven has shown for the first time that dysfunctional mitochondria in brain cells can lead to learning disabilities. The link between ...

Parkinson's & Movement disorders created May 17, 2013 | popularity 4 / 5 (2) | comments 0

Binding sites for LIN28 protein found in thousands of human genes

A study led by researchers at the UC San Diego Stem Cell Research program and funded by the California Institute for Regenerative Medicine (CIRM) looks at an important RNA binding protein called LIN28, which ...

Genetics created Sep 04, 2012 | popularity 4.3 / 5 (6) | comments 0 | with audio podcast

Scientists link excess sugar to cancer

Sugars are needed to provide us with energy and in moderate amounts contribute to our well-being. Sustained high levels of sugars, as is found in diabetics, damages our cells and now is shown that can also ...

Medical research created Feb 01, 2013 | popularity 4.7 / 5 (19) | comments 12 | with audio podcast

Uncovering the genome's regulatory code

Since the sequencing of the human genome in 2001, all our genes – around 20,000 in total – have been identified. But much is still unknown – for instance where and when each is active. Next to each ...

Genetics created Sep 10, 2012 | popularity 5 / 5 (1) | comments 1 | with audio podcast

Cell death discovery suggests new ways to protect female fertility

Melbourne researchers have identified a new way of protecting female fertility, offering hope to women whose fertility may be compromised by the side-effects of cancer therapy or by premature menopause.

Medical research created Sep 22, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Target for obesity drugs comes into focus

(Medical Xpress)—Researchers at the University of Michigan have determined how the hormone leptin, an important regulator of metabolism and body weight, interacts with a key receptor in the brain.

Medical research created Oct 11, 2012 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Team uncovers new insight into cell development and cancer

Long-standing research efforts have been focused on understanding how stem cells, cells capable of transforming into any type of cell in the body, are capable of being programmed down a defined path to contribute ...

Cancer created Dec 27, 2012 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Researchers reveal crucial immune fighter role of the STING protein

Researchers at Weill Cornell Medical College have unlocked the structure of a key protein that, when sensing certain viruses and bacteria, triggers the body's immediate immune response.

Medical research created Jun 18, 2012 | popularity 5 / 5 (4) | comments 0 | with audio podcast

Does presence of oxidants early in life help determine life span?

Why do we age, and what makes some of us live longer than others? For decades, researchers have been trying to answer these questions by elucidating the molecular causes of aging.

Medical research created Jul 19, 2012 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Scientists create roadmap to metabolic reprogramming for aging

In efforts to understand what influences life span, cancer and aging, scientists are building roadmaps to navigate and learn about cells at the molecular level.

Medical research created Nov 29, 2012 | popularity 5 / 5 (8) | comments 0 | with audio podcast

Researchers ID gene that turns carbs into fat: Discovery could help development of treatment for fatty liver, diabetes

A gene that helps the body convert that big plate of holiday cookies you just polished off into fat could provide a new target for potential treatments for fatty liver disease, diabetes and obesity.

Genetics created Dec 06, 2012 | popularity 5 / 5 (3) | comments 1 | with audio podcast

Methylome modifications offer new measure of our 'biological' age

Women live longer than men. Individuals can appear or feel years younger – or older – than their chronological age. Diseases can affect our aging process. When it comes to biology, our clocks clearly tick differently.

Medical research created Nov 21, 2012 | popularity 5 / 5 (5) | comments 0 | with audio podcast

Inhibiting enzymes in the cell may lead to development and proliferation of cancer cells

Blocking certain enzymes in the cell may prevent cancer cell division and growth, according to new findings from researchers at the Graduate School of Biomedical Sciences at the Icahn School of Medicine at Mount Sinai. The ...

Cancer created Apr 25, 2013 | popularity 5 / 5 (1) | comments 1