Nature Methods

New automated imaging to greatly speed whole-brain mapping efforts

A new technology developed by neuroscientists at Cold Spring Harbor Laboratory (CSHL) transforms the way highly detailed anatomical images can be made of whole brains. Until now, means of obtaining such images ...

Medical research created Jan 15, 2012 | popularity 4.3 / 5 (14) | comments 3 | with audio podcast

Scientists develop alternative to gene therapy: The technique points to safer, simpler potential HIV treatment

Scientists at The Scripps Research Institute have discovered a surprisingly simple and safe method to disrupt specific genes within cells. The scientists highlighted the medical potential of the new technique by demonstrating ...

Medical research created Jul 01, 2012 | popularity 5 / 5 (9) | comments 0 | with audio podcast

An 'off' switch for pain: Chemists build light-controlled neural inhibitor

Pain? Just turn it off! It may sound like science fiction, but researchers based in Munich, Berkeley and Bordeaux have now succeeded in inhibiting pain-sensitive neurons on demand, in the laboratory. The crucial element in ...

Medical research created Feb 22, 2012 | popularity 5 / 5 (6) | comments 0 | with audio podcast

Researchers image most of vertebrae brain at single cell level (w/ video)

(Medical Xpress)—Misha Ahrens and Philipp Keller, researchers with the Howard Hughes Medical Institute have succeeded in making a near real-time video of most of a zebrafish's brain showing individual neuron ...

Neuroscience created Mar 20, 2013 | popularity 5 / 5 (5) | comments 0 | with audio podcast report

Research team takes new approach to studying differences between human and monkey brains

(Medical Xpress) -- In order to provide more insight into how human and monkey brains are similar and how they’re different, a research team has taken a different approach to studying both to find out ...

Neuroscience created Feb 06, 2012 | popularity 4.6 / 5 (5) | comments 2 | with audio podcast report

Scientists aim to analyse a whole mouse brain under the electron microscope

What happens in the brain when we see, hear, think and remember? To be able to answer questions like this, neuroscientists need information about how the millions of neurons in the brain are connected to ...

Neuroscience created Oct 23, 2012 | popularity 3.5 / 5 (6) | comments 1 | with audio podcast

'Brainbow,' version 2.0: Researchers refine breakthrough system for producing images of brain, nervous system

(Medical Xpress)—The breakthrough technique that allowed scientists to obtain one-of-a-kind, colorful images of the myriad connections in the brain and nervous system is about to get a significant upgrade.

Neuroscience created May 16, 2013 | popularity 5 / 5 (3) | comments 0 | with audio podcast

Discovery offers unprecedented look at regulation of gene expression

(Medical Xpress)—A groundbreaking technique developed at the University of Virginia School of Medicine is allowing scientists to examine histone modifications of genetic loci – a process that regulates gene expression ...

Medical research created Jan 25, 2013 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Gene mapping reveals architecture that controls expression of genes responsible for our sense of smell

Within the nasal cavity, millions of sensory neurons in a postage-stamp-sized patch of tissue called the olfactory epithelium control our sense of smell. Thanks to the exquisitely controlled expression of ...

Genetics created May 18, 2012 | popularity 5 / 5 (1) | comments 1

New method may allow personalized clinical trial for cancer therapies

A new tool to observe cell behavior has revealed surprising clues about how cancer cells respond to therapy – and may offer a way to further refine personalized cancer treatments.

Cancer created Aug 13, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Uncovering a flaw in drug testing for chronic anxiety disorder

Pre-clinical trials—the stage at which medications or therapies are tested on animals like laboratory mice—is a crucial part of drug development. It's only then that scientists can assess benefits and side effects before ...

Medical research created Dec 13, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast