PLoS Biology
PLoS Biology is a peer-reviewed scientific journal covering all aspects of biology. Publication began on October 13, 2003. It was the first journal of the Public Library of Science. All content in PLoS Biology is published under the Creative Commons "by-attribution" license. To fund the journal, the publication s business model requires that, in most cases, authors will pay publication costs. In addition to research articles, PLoS Biology publishes online e-letters in which readers provide comments on articles. According to the Journal Citation Reports, the journal has a 2009 impact factor of 12.916, ranking it first in the category Biology . Mike Taylor of Discover Magazine said in 2012 that while PLoS Biology has a high impact factor, "PLoS has de-emphasized this traditional, problematic measure, so you won’t find this fact blazoned across their website." The current editor-in-chief is Jonathan Eisen (University of California, Davis). Due to their free licensing, files from PLoS Biology can be reused in places other than the original article, e.g. to illustrate Wikipedia articles.
A new strategy required in the search for Alzheimer's drugs?
In the search for medication against Alzheimer's disease, scientists have focused – among other factors – on drugs that can break down Amyloid beta (A-beta). After all, it is the accumulation of A-beta that causes the ...
Alzheimer's disease & dementia
May 24, 2013 |
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Scientists identify important regulator for synapse stability and plasticity
(Medical Xpress)—Using the fruit fly as a model organism, neurobiologists from the Friedrich Miescher Institute for Biomedical Research have identified the L1-type CAM neuroglian as an important regulator ...
Neuroscience
Apr 25, 2013 |
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Researchers discover new explanation for diabetes and poor growth
A group of researchers from the University of Copenhagen has taken a significant step towards understanding the reasons for both diabetes and growth hormone deficiency. Their new discoveries centre on the body's ability to ...
Medical research
Apr 23, 2013 |
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Molecular signaling in early placenta formation gives clues to causes of pregnancy complications
Understanding the molecular control of placenta formation, the organ which enables fetal growth, is critical in diagnosing and treating related pregnancy complications. A group of scientists at the Chinese Academy of Sciences, ...
Medical research
Apr 16, 2013 |
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Manipulating calcium accumulation in blood vessels may provide a new way to treat heart disease
Hardening of the arteries, or atherosclerosis, is the primary cause of heart disease. It is caused by calcium accumulation in the blood vessels, which leads to arteries becoming narrow and stiff, obstructing blood flow and ...
Cardiology
Apr 09, 2013 |
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Scientists discover new mechanisms for relaxing airways using bitter tasting substances
That kale and bitter melon you are eating may someday save your life. An interdisciplinary team of scientists at the University of Massachusetts Medical School have taken a step forward in understanding how the substances ...
Medical research
Mar 05, 2013 |
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Study in mice yields Angelman advance
In a new study in mice, a scientific collaboration centered at Brown University lays out in unprecedented detail a neurological signaling breakdown in Angelman syndrome, a disorder that affects thousands ...
Medical research
Feb 13, 2013 |
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Chance finding reveals new control on blood vessels in developing brain
(Medical Xpress)—Zhen Huang freely admits he was not interested in blood vessels four years ago when he was studying brain development in a fetal mouse.
Medical research
Jan 24, 2013 |
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Your brain on Big Bird: Sesame Street helps to reveal patterns of neural development
Using brain scans of children and adults watching Sesame Street, cognitive scientists are learning how children's brains change as they develop intellectual abilities like reading and math.
Neuroscience
Jan 03, 2013 |
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The factor that could influence future breast cancer treatment
Australian scientists have shown in the laboratory how a 'transcription factor' causes breast cancer cells to develop an aggressive subtype that lacks sensitivity to estrogen and does not respond to known anti-estrogen therapies. ...
Cancer
Dec 27, 2012 |
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Scientists discover how HIV virus gains access to carrier immune cells to spread infection
Scientists from the AIDS Research Institute IrsiCaixa have identified how HIV, the virus that causes AIDS, enters the cells of the immune system enabling it to be dispersed throughout an organism. The new ...
HIV & AIDS
Dec 18, 2012 |
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Crag keeps the light 'fantastic' for photoreceptors
The ability of the eye of a fruit fly (Drosophila melanogaster) to respond to light depends on a delicate ballet that keeps the supply of light sensors called rhodopsin constant as photoreceptors turn on and off in respon ...
Neuroscience
Dec 04, 2012 |
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Human obedience: The myth of blind conformity
In the 1960s and 1970s, classic social psychological studies were conducted that provided evidence that even normal, decent people can engage in acts of extreme cruelty when instructed to do so by others. However, in an essay ...
Psychology & Psychiatry
Nov 20, 2012 |
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The evolution of human intellect: Human-specific regulation of neuronal genes
A new study published November 20 in the open-access journal PLOS Biology has identified hundreds of small regions of the genome that appear to be uniquely regulated in human neurons. These regulatory differences distinguish us fro ...
Genetics
Nov 20, 2012 |
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How does the brain measure time?
Researchers at the University of Minnesota's Center for Magnetic Resonance Research (CMRR) have found a small population of neurons that is involved in measuring time, which is a process that has traditionally been difficult ...
Neuroscience
Oct 30, 2012 |
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