PLoS Biology

Psychology & Psychiatry

Sleepless and selfish: Lack of sleep makes us less generous

Humans help each other—it's one of the foundations of civilized society. But a new study by scientists at the University of California, Berkeley, reveals that a lack of sleep blunts this fundamental human attribute, with ...

Genetics

New antibiotic resistance genes identified in tuberculosis

A massive analysis of more than 10,000 different Mycobacterium tuberculosis bacteria isolates from 23 countries has revealed new genes associated with resistance to 13 first- and second-line new and repurposed antibiotics. ...

Neuroscience

Sentences have their own timing in the brain

The brain links incoming speech sounds to knowledge of grammar, which is abstract in nature. But how does the brain encode abstract sentence structure? In a neuroimaging study published in PLOS Biology, researchers from the ...

Neuroscience

In Krabbe disease, neurons may bring about their own destruction

The gene defect underlying Krabbe disease causes degeneration of neurons directly, independent of its effects on other cell types, according to a new study publishing July 5 in the open-access journal PLOS Biology by Daesung ...

Medical research

A new hope for a therapy against retinitis pigmentosa

Retinitis pigmentosa, a degenerative genetic disease of the eye, is characterized by progressive vision loss, usually leading to blindness. In some patients, structural defects in the photoreceptor cells have been observed, ...

Medications

New antibiotics could tackle drug-resistant tuberculosis bacteria

Infection by Mycobacterium tuberculosis kills 1.5 million people worldwide every year. Antibiotics to treat TB exist, but in recent years, multi-drug resistant (MDR), extensively drug-resistant (XDR) and totally drug-resistant ...

Diseases, Conditions, Syndromes

Potential strategy to reduce fatigue after COVID-19 vaccination

Despite their strong effectiveness against SARS-CoV-2, mRNA-based COVID-19 vaccines are associated with adverse post-vaccination effects, such as fatigue; how can this be avoided? In a new study publishing May 31st in the ...

Medical research

Frozen testicular tissue still viable after two decades

Male testis tissue that is cryopreserved can be reimplanted after more than 20 years and will go on to make viable sperm, according to a new study in rodents in the open-access journal PLOS Biology by Eoin Whelan of the School ...

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