Proceedings of the National Academy of Sciences

Radiology & Imaging

Targeted MRI detects chronic liver disease

Chronic liver diseases such as hepatitis, liver cirrhosis, and hepatocellular carcinoma are a major cause of morbidity and mortality worldwide. Fibrosis—the thickening and scarring of connective tissue—plays a major role ...

Oncology & Cancer

Scientists show reprogrammed fat cells support tumor growth

Mutations of the tumor suppressor p53 not only have a growth-promoting effect on the cancer cells themselves, but also influence the cells in the tumor's microenvironment. Scientists at the German Cancer Research Center (DKFZ) ...

Oncology & Cancer

Researchers uncover on/off switch for breast cancer metastasis

Despite their promise, immunotherapies fail to treat many cancers, including over 80% of some of the most advanced breast cancers. And many of those patients who do respond still experience metastases eventually. New research ...

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