Science Express

New vaccine-design approach targets HIV and other fast-mutating viruses

A team led by scientists from The Scripps Research Institute (TSRI) and the International AIDS Vaccine Initiative (IAVI) has unveiled a new technique for vaccine design that could be particularly useful against ...

HIV & AIDS created Mar 28, 2013 | popularity 4.8 / 5 (6) | comments 1 | with audio podcast

Study reveals how serotonin receptors can shape drug effects from LSD to migraine medication

A team including scientists from The Scripps Research Institute (TSRI), the University of North Carolina at Chapel Hill and the Chinese Academy of Sciences has determined and analyzed the high-resolution ...

Medical research created Mar 21, 2013 | popularity 4.8 / 5 (5) | comments 0 | with audio podcast

New mutations driving malignant melanoma discovered

Two new mutations that collectively occur in 71 percent of malignant melanoma tumors have been discovered in what scientists call the "dark matter" of the cancer genome, where cancer-related mutations haven't ...

Cancer created Jan 24, 2013 | popularity not rated yet | comments 0 | with audio podcast

Researchers describe elusive replication machinery of flu viruses

Scientists at The Scripps Research Institute (TSRI) have made a major advance in understanding how flu viruses replicate within infected cells. The researchers used cutting-edge molecular biology and electron-microscopy ...

Medical research created Nov 22, 2012 | popularity 5 / 5 (6) | comments 0 | with audio podcast

Study solves birth and migration mysteries of cortex's powerful inhibitors, 'chandelier' cells

A team at CSHL for the 1st time reveals the birth timing and embryonic origin of a critical class of inhibitory brain cells called chandelier cells, tracing the specific paths they take during early development into the cerebral ...

Neuroscience created Nov 22, 2012 | popularity 5 / 5 (3) | comments 2 | with audio podcast

Brain's code for visual working memory deciphered in monkeys

The brain holds in mind what has just been seen by synchronizing brain waves in a working memory circuit, an animal study supported by the National Institutes of Health suggests. The more in-sync such electrical ...

Neuroscience created Nov 02, 2012 | popularity 5 / 5 (1) | comments 1 | with audio podcast

Wnt5a protein critical to gut lining repair

Scientists at Washington University School of Medicine in St. Louis have identified a protein essential to repairing the intestine's inner lining.

Medical research created Sep 06, 2012 | popularity 4 / 5 (3) | comments 0 | with audio podcast

Toward 'universal' vaccine: Scientists describe antibodies that protect against large variety of flu viruses

A team led by scientists at The Scripps Research Institute and Crucell Vaccine Institute in the Netherlands describes three human antibodies that provide broad protection against Influenza B virus strains. ...

Medical research created Aug 09, 2012 | popularity 5 / 5 (5) | comments 0 | with audio podcast

Promising treatment for progeria within reach

Pharmaceuticals that inhibit a specific enzyme may be useful in treating progeria, or accelerated aging in children. A new study performed at the Sahlgrenska Academy indicates that the development of progeria ...

Diseases, Conditions, Syndromes created May 16, 2013 | popularity 5 / 5 (4) | comments 0 | with audio podcast

Finding a new way to manage infections

(Medical Xpress)—Waging an immunological war against a pathogen is not the body's only way to survive an infection. Sometimes tolerance, or learning to live with an invader, can be just as important. In tolerance the body ...

Immunology created Apr 29, 2013 | popularity 4.7 / 5 (3) | comments 0 | with audio podcast

Scientists discover gene mutation that causes children to be born without spleen

The spleen is rarely noticed, until it is missing. In children born without this organ, that doesn't happen until they become sick with life-threatening bacterial infections. An international team of researchers led by scientists ...

Genetics created Apr 11, 2013 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Mechanism of mutant histone protein in childhood brain cancer revealed

(Medical Xpress)—Most cancer treatments are blunt. In an attempt to eradicate tumors, oncologists often turn to radiation or chemotherapy, which can damage healthy tissue along with the cancerous growths. ...

Cancer created Apr 01, 2013 | popularity 5 / 5 (1) | comments 0 | with audio podcast

New flu drug stops virus in its tracks

A new class of influenza drug has been shown effective against drug-resistant strains of the flu virus, according to a study led by University of British Columbia researchers.

Medical research created Feb 21, 2013 | popularity 4.6 / 5 (11) | comments 0 | with audio podcast

Translation error tracked in the brain of dementia patients

In certain dementias silent areas of the genetic code are translated into highly unusual proteins by mistake. An international team of scientists including researchers from the German Center for Neurodegenerative ...

Neuroscience created Feb 07, 2013 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Ethicists provide framework supporting new recommendations on reporting incidental findings in gene sequencing

In a paper published in Science Express, a group of experts led by bioethicists in the Center for Medical Ethics and Health Policy at Baylor College of Medicine provide a framework for the new American College of Medical Geneti ...

Genetics created May 16, 2013 | popularity not rated yet | comments 0