Bioengineering students' invention may help diagnose painful eye condition

April 25, 2011
Rice University senior Austin Edwards wears the modified, sensor-laden laboratory goggles designed by a Rice student engineering team as part of a device for the diagnosis of dry eye. (Credit Jeff Fitlow/Rice University)

Rice University bioengineering students responded to an ophthalmologist's cry for help with a device to diagnose dry eye, the itching and burning sensation that results when a person doesn't produce enough tears or the tears evaporate too quickly.

A team of five seniors made a portable unit that controls the air around a patient's eyes so doctors can study and treat those who suffer from this painful condition.

Stephen Pflugfelder, the James and Margaret Elkins Chair and professor of at Baylor College of Medicine's Cullen Eye Institute, approached Rice to invent a device to help clinicians standardize a testing regime for dry eye.

This video is not supported by your browser at this time.
A team of five Rice University seniors made a portable unit that controls the air around a patient's eyes so doctors can study and treat those who suffer from painful dry eye conditions. Credit: Mike Williams/Rice University

"He wanted a way to control temperature, humidity and air flow all around the eyes and record it over time so he could track changes in their dryness," said Daniel Hays, a member of Team ClimaTears, the student group that included Austin Edwards, Amanda Shih, Anastasia Alex and Michelle Kerkstra.

The students' solution incorporates a modified and padded set of laboratory with embedded data that monitor temperature, relative humidity, air flow and blink rate over an hour and a half. A cable carries data saved every 10 seconds to a small box that includes controls and conditioning equipment. A separate hose carries air to the goggles.

The goggles keep the humidity of air around the eyes between 40 and 15 percent -- "about as low as we can go without hurting patients," Alex said.

"We're exacerbating the symptoms so doctors can see them," Hays explained.

Normal patients will produce tears, he said, but those who suffer will exhibit symptoms, which will give clues about how to treat them. Follow-up sessions with the goggles will let doctors see how well the treatment is working.

"With this, we're putting the power in the hands of clinicians, which is very appealing to them," Shih said.

"We did a lot of research on the ocular test they currently perform to help us analyze the data we collected," Alex said. "We know there's still a lot to be done."

"We hope our device will create a gold standard for diagnosis," Kerkstra said.

The team and Pflugfelder spent two weeks this spring testing patients at the Alkek Eye Center in Houston and will continue this summer. The students hope the larger trial will lead to an academic paper -- a fine reward for spending nearly 2,000 hours developing the goggles over the course of their final year at Rice.

Their work has already paid dividends. The students won the grand prize, $1,500, in the second annual Rice Alliance-George R. Brown School of Engineering Senior Design Elevator Pitch Competition last November, and more recently $500 for the Best Health-Related Engineering Design Project at the School of Engineering Design Showcase held April 14.

The team's faculty advisers were Renata Ramos, a Rice lecturer in bioengineering, and Maria Oden, professor in the practice of engineering education and director of Rice's Oshman Engineering Design Kitchen, where the goggles were developed.

Related Stories

Recommended for you

New 'Tissue Velcro' could help repair damaged hearts

August 28, 2015

Engineers at the University of Toronto just made assembling functional heart tissue as easy as fastening your shoes. The team has created a biocompatible scaffold that allows sheets of beating heart cells to snap together ...

Fertilization discovery: Do sperm wield tiny harpoons?

August 26, 2015

Could the sperm harpoon the egg to facilitate fertilization? That's the intriguing possibility raised by the University of Virginia School of Medicine's discovery that a protein within the head of the sperm forms spiky filaments, ...

Research identifies protein that regulates body clock

August 26, 2015

New research into circadian rhythms by researchers at the University of Toronto Mississauga shows that the GRK2 protein plays a major role in regulating the body's internal clock and points the way to remedies for jet lag ...

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.