Childhood eczema and hay fever leads to adult allergic asthma

(PhysOrg.com) -- Children who have eczema, particularly when occurring with hay fever, are nine times more likely to develop allergic asthma in their 40s, a new study reveals.

The study was conducted by the University of Melbourne, the Murdoch Childrens Research Institute, Menzies Research Institute and Monash University. 

Published online in the Journal of Allergy and Clinical Immunology, the study reported on evidence from a clinical study of around 1400 grown up participants in the fifth decade follow-up of the Tasmanian Longitudinal Health Study (TAHS) which is the largest of its kind in the world.

In the TAHS, participants were assessed about their allergies and childhood environment in 1968, at seven years of age, and were followed up in 2004, at the age of 44.

Lead author Pamela Martin, a University of Melbourne PhD student based at the Murdoch Children Research Institute analysed the survey and skin prick testing data collected in the clinical study for the evidence of childhood eczema and leading to adult . 


 She said “In this study we see that childhood eczema, particularly when hay fever also occurs, is a very strong predictor of who will suffer from allergic asthma in adult life.”

 “The implications of this study are that prevention and rigorous treatment of childhood eczema and hay fever may prevent the persistence and development of asthma.”

She also said this is the first study to distinguish between allergic and non-allergic asthma and their occurrence after childhood eczema and hay fever, as part of a sequence of allergic illnesses dubbed the ‘atopic march’.

Associate Professor Shyamali Dharmage, principal investigator of the TAHS and from the University of Melbourne’s School of Population Health said currently few interventions are trialled to halt this march from childhood allergies to asthma.

“If successful strategies to stop the ‘atopic march’ are identified, this could ultimately save lives and health care costs related to asthma management and treatment.”

The researchers estimate that up to 30 per cent of current within the larger population sample could be attributed to a history of childhood and hay fever.

add to favorites email to friend print save as pdf

Related Stories

Eczema in early childhood and psychological problems

Feb 10, 2010

Eczema in early childhood may influence behavior and mental health later in life. This is a key finding of a prospective birth cohort study to which scientists of Helmholtz Zentrum München contributed. In cooperation with ...

Allergic disease linked to irritable bowel syndrome

Jan 30, 2008

Adults with allergy symptoms report a high incidence of Irritable Bowel Syndrome (IBS), suggesting a link between atopic disorders and IBS according to a study published this month in Annals of Allergy, Asthma & Immunology, ...

Recommended for you

Ebola vaccine promising in first human trials

3 hours ago

Researchers say they are one step closer to developing an Ebola vaccine, with a Phase 1 trial showing promising results, but it will be months at the earliest before it can be used in the field.

At one month, US Ebola monitors finding no cases

6 hours ago

The U.S. program that requires weeks of monitoring for travelers from African countries with Ebola reaches the one-month mark Thursday. And so far, no cases of the disease have turned up.

EU calls for 5,000 doctors to fight Ebola

7 hours ago

The European Commission called for 5,000 doctors to be sent from EU states to combat west Africa's Ebola epidemic, a European source with knowledge of the matter said on Wednesday.

User comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.