UCSF analysis shows newer surgery for neck pain may be better

April 11, 2011 in Other

A new surgery for cervical disc disease in the neck may restore range of motion and reduce repeat surgeries in some younger patients, according to a team of neurosurgeons from the University of California, San Francisco (UCSF) and several other medical centers that analyzed three large, randomized clinical trials comparing two different surgeries.

More than 200,000 Americans undergo surgery every year to alleviate pain and from the debilitating condition caused by herniated discs in the neck. For some, the team found, arthroplasty may work better.

The results do not suggest that the older surgery is ineffective or unsafe, but that arthroplasty is a viable option for some.

"For people younger than 50 who have cervical disc disease, arthroplasty is a good option," said Praveen Mummaneni, MD, of the Department of at UCSF.

Mumaneni and his colleagues are presenting their analysis today at the 79th Annual Scientific Meeting of the American Association of Neurological Surgeons in Denver.

Why Fewer Is Better

is not cheap and requires a patient to be placed under and a surgical team to perform the operation in a sterile room. They are typically reserved for patients who have failed to respond to other measures such as physical therapy or drugs, such as steroids.

For decades, the standard of care in this country was a procedure called anterior cervical discectomy and fusion. In this surgery, a surgeon cuts through the front of the neck, accessing the spine and removing the herniated disc, then replacing it with a piece of bone and a plate in the neck. That creates a solid union – or fusion – between two or more vertebrae to strengthen the spine.

Arthroplasty also begins with a surgery to remove the herniated disc. But instead of fusing the spine, the surgeon replaces the missing disc with an artificial one made of steel, plastic or titanium. The idea is that the artificial disc will provide more spine mobility after surgery and less stress on adjacent discs.

While arthroplasty has become more widely used in the United States since the U.S. Food & Drug Administration approved several models of artificial discs in the last few years, it is still performed less often than in Europe, where the procedure has been available for more than a decade.

Here in the United States, the older, surgical fusion technique remains more common – in part because not all insurance companies pay for the newer procedure, as is the case in California.

Both techniques have occasional failures. In the fusion surgery, the bone may not heal, requiring further fusion surgery months or years later. In the arthroplasty surgery, the artificial disk may loosen or not fit well and may need to be replaced.

"Surprising" Results

The new analysis looked at three randomized clinical trials that enrolled 1,213 patients with cervical disc disease at medical centers across the United States – including UCSF.

In the trials, 621 patients received an artificial cervical disc and 592 patients were treated with spinal fusion. The analysis looked at outcomes two years after surgery.

The results were surprising, Mummaneni said: "While the two-year surgical results for both techniques were excellent, the rate of repeat surgery is lower for arthroplasty than for fusion at the two-year timepoint."

Provided by University of California, San Francisco search and more info website

not rated yet  

Rank not rated yet
Relevant PhysicsForums posts

More news stories

ACP issues recommendations for management of high blood glucose in hospitalized patients

High blood glucose is associated with poor outcomes in hospitalized patients, and use of intensive insulin therapy (IIT) to control hyperglycemia is a common practice in hospitals. But the recent evidence does not show a ...

Other created May 24, 2013 | popularity 4 / 5 (1) | comments 0

Future doctors unaware of their obesity bias

Two out of five medical students have an unconscious bias against obese people, according to a new study by researchers at Wake Forest Baptist Medical Center. The study is published online ahead of print in the Journal of ...

Other created May 23, 2013 | popularity not rated yet | comments 0

Plastic realistic: Medical students to use plastinated human bodies for anatomy learning

Nanyang Technological University's (NTU) new medical school will be pioneering the use of plastinated bodies for medical education in Singapore.

Other created May 23, 2013 | popularity not rated yet | comments 0

Survey points out deficiencies in addictions training for medical residents

A 2012 survey of internal medicine residents at Massachusetts General Hospital (MGH) – one of the nation's leading teaching hospitals – found that more than half rated the training they had received in addiction and other ...

Other created May 22, 2013 | popularity 5 / 5 (1) | comments 0

Early use of tracheostomy for mechanically ventilated patients not associated with improved survival

For critically ill patients receiving mechanical ventilation, early tracheostomy (within the first 4 days after admission) was not associated with an improvement in the risk of death within 30 days compared to patients who ...

Other created May 21, 2013 | popularity not rated yet | comments 0


Engineered cytomegalovirus protects monkeys from HIV equivalent

(Medical Xpress)—A new study by researchers in the US has shown that an ancient virus can be modified to help in the fight against the simian immunodeficiency virus SIV, which is the equivalent in monkeys ...

Researchers identify first drug targets in childhood genetic tumor disorder

Two mutations central to the development of infantile myofibromatosis (IM)—a disorder characterized by multiple tumors involving the skin, bone, and soft tissue—may provide new therapeutic targets, according to researchers ...

Hormone levels may provide key to understanding psychological disorders in women

Women at a particular stage in their monthly menstrual cycle may be more vulnerable to some of the psychological side-effects associated with stressful experiences, according to a study from UCL.

Going live: Immune cell activation in multiple sclerosis

Biological processes are generally based on events at the molecular and cellular level. To understand what happens in the course of infections, diseases or normal bodily functions, scientists would need to ...

Help at hand for people with schizophrenia

How can healthy people who hear voices help schizophrenics? Finding the answer for this is at the centre of research conducted at the University of Bergen.

Alzheimer's disease, the soft target of the euthanasia debate

(Medical Xpress)—The way Alzheimer's disease is portrayed by advocacy groups and the media is having undue influence on the euthanasia debate, according to a Deakin University nursing ethics professor.