Brain training increases dopamine release

It is known that training can improve working memory. In a new study in Science, researchers from Karolinska Institutet, Umeå University, Åbo Akademi University, and the University of Turku show for the first time that working-memory training is associated with an increased release of the neurotransmitter dopamine in specific brain regions.

" training resulted in increased dopamine release in the caudate, a region located below the neocortex, in which the dopaminergic influx is particularly large", says Lars Bäckman, Professor at Karolinska Institutet, and one of the scientists behind the study. "This observation demonstrates the importance of dopamine for improving working-memory performance."

In the study, 10 young Finnish men were trained in updating working memory for five weeks by means of a letter-memory task. The participants were presented with 7 to 15 letters during 45 minutes three times per week on a screen that was turned off after presentation. The task was to remember the last four letters in the sequence in correct order. (The training programme can be found on-line, see link further down)

Compared to a control group that did not receive any training, the trained group showed a gradual improvement of working-memory performance. Results from a PET scan demonstrated an increased release of dopamine in the caudate after training. In addition, dopamine release was seen during the letter-memory task also before training; this release increased markedly after training.

Further, improvements after training were demonstrated in an untrained task that also requires updating.

"These findings suggest that the improved working memory generally", says Professor Lars Nyberg at Umeå University.

Related Stories

Cognitive training can alter the biochemistry of the brain

Feb 06, 2009

(PhysOrg.com) -- Researchers at the Swedish medical university Karolinska Institutet have shown for the first time that the active training of the working memory brings about visible changes in the number of dopamine receptors ...

A brain training exercise that really does work

May 30, 2011

(Medical Xpress) -- Forget about working crossword puzzles and listening to Mozart. If you want to improve your ability to reason and solve new problems, just take a few minutes every day to do a maddening little exercise ...

Recommended for you

Screenagers face troubling addictions from an early age

6 hours ago

In 1997, Douglas Rushkoff boldly predicted the emergence a new caste of tech-literate adolescents. He argued that the children of his day would soon blossom into "screenagers", endowed with effortless advantages over their parents, ...

Better memory at ideal temperature

7 hours ago

People's working memory functions better if they are working in an ambient temperature where they feel most comfortable. That is what Leiden psychologists Lorenza Colzato and Roberta Sellaro conclude after having conducted ...

User comments