Research examines over-the-counter drug's effect on chemo's side effects
New research has potential to alleviate the side effects of cancer treatments.
Beth Faiman MSN, CNP, a doctoral candidate at the Frances Payne Bolton School of Nursing at Case Western Reserve University, is studying whether an over-the-counter medication could ease chemotherapy side effects for people with blood and bone marrow cancers.
Faiman has worked as a nurse practitioner since 1994 at the Cleveland Clinic Taussig Cancer Center with patients diagnosed with multiple myeloma. Working with doctors who treat patients and also do research inspired Faiman, she says. "I wanted to be a nurse researcher, and like the doctors, treat patients but also do research to help them."
Faiman needed her PhD to do it. She enrolled in the doctoral program at the Frances Payne Bolton School of Nursing.
As a nurse practitioner and a delegate for the International Myeloma Foundation Nurse Leadership Board, Faiman observed that her patients, with multiple myeloma are surviving cancer with new drug treatments. Unfortunately the treatments caused peripheral neuropathy the nerve damage that leaves some patients with severe numbing, burning or tingling in the hands and feet.
With support from two grantsone from the Oncology Nursing Society and the other from the National Institutes of Health's National Research Service Award program, she will lead the study, "The effect of adjuvant therapy on cancer neuropathy symptoms."
Faiman will enroll 60 patients with multiple myeloma in a double-blind study in which half of the group will receive Glutamine, which has helped some colon and breast cancer patients with their neuropathy. The other half will receive a placebo.
Glutamine can be bought over the counter at drug stores. It is an agent that some patients say alleviates painful symptoms. In cancers like breast and colon, some patients have seen an improvement in these symptoms.
Faiman's concern is that patients may be taking a medication that would interfere with their chemotherapy or that would yield no benefits.
"These individuals with peripheral neuropathy are at risk for falls and other dangers," Faiman says.
Few researchers have yet studied Glutamine's effectiveness, Faiman says, especially, with patients diagnosed with multiple myeloma. She hopes her pioneering effort may give patients additional information as the work to beat cancer and she hopes it will bring her one step closer to the nurse-researcher she aims to be.
Provided by Case Western Reserve University
- Drug combination shows promise for newly diagnosed blood cancer patients, study finds Dec 09, 2010 | not rated yet | 0
- Drug shows positive responses, low side-effects in multiple myeloma Dec 07, 2009 | not rated yet | 0
- Treatment with anti-anemia drugs may not be safe for multiple myeloma patients Aug 04, 2008 | not rated yet | 0
- Multiple myeloma patients experience high response rate with new 3-drug combination Dec 06, 2009 | not rated yet | 0
- Study shows that administering calcium and magnesium effectively reduces neurological sensitivity May 16, 2008 | not rated yet | 0
- Motion perception revisited: High Phi effect challenges established motion perception assumptions Apr 23, 2013 | 3 / 5 (2) | 2
- Anything you can do I can do better: Neuromolecular foundations of the superiority illusion (Update) Apr 02, 2013 | 4.5 / 5 (11) | 5
- The visual system as economist: Neural resource allocation in visual adaptation Mar 30, 2013 | 5 / 5 (2) | 9
- Separate lives: Neuronal and organismal lifespans decoupled Mar 27, 2013 | 4.9 / 5 (8) | 0
- Sizing things up: The evolutionary neurobiology of scale invariance Feb 28, 2013 | 4.8 / 5 (10) | 14
Why is zone 1 in liver more prone to ischemic injury?
May 23, 2013 Hi, Is it because around central vein, there is only deoxygenated blood from the vein where as in the periphery there is hepatic artery. Also why...
How can there be villous adenoma in colon, if there are no villi there
May 22, 2013 As title suggest. Thanks :smile:
How can there be a term called "intestinal metaplasia" of stomach
May 21, 2013 Hello everyone, Ok Stomach's normal epithelium is simple columnar, now in intestinal type of adenocarcinoma of stomach it undergoes "intestinal...
Pressure-volume curve: Elastic Recoil Pressure don't make sense
May 18, 2013 From pressure-volume curve of the lung and chest wall (attached photo), I don't understand why would the elastic recoil pressure of the lung is...
If you became brain-dead, would you want them to pull the plug?
May 17, 2013 I'd want the rest of me to stay alive. Sure it's a lousy way to live but it beats being all-the-way dead. Maybe if I make it 20 years they'll...
MRI bill question
May 15, 2013 Dear PFers, The hospital gave us a $12k bill for one MRI (head with contrast). The people I talked to at the hospital tell me that they do not...
- More from Physics Forums - Medical Sciences
More news stories
In recent years, microRNAs (miRNAs) and other non-coding RNAs are small molecules that help control the expression of specific proteins. In recent years they have emerged as disease biomarkers. miRNA profiles have been used ...
Cancer May 24, 2013 | not rated yet | 0
Cancer cells spread and grow by avoiding detection and destruction by the immune system. Stimulation of the immune system can help to eliminate cancer cells; however, there are many factors that cause the immune system to ...
Cancer May 24, 2013 | 5 / 5 (1) | 0
Researchers from London's Kingston University have begun a two-year study which could help prolong the lives of people with colorectal tumours.
Cancer May 24, 2013 | 5 / 5 (1) | 0
Transformative research from Western University has identified new hormones in the body which may suppress breast cancer and stimulate the regression of breast tumors.
Cancer May 24, 2013 | 5 / 5 (2) | 0
(Medical Xpress)—Curtin University researchers have found evidence that targeting specific cells in the body can reverse the effects of cancer on the immune system.
Cancer May 24, 2013 | 5 / 5 (4) | 0
Coenzyme Q10 decreases all cause mortality by half, according to the results of a multicentre randomised double blind trial presented today at Heart Failure 2013 congress. It is the first drug to improve heart failure mortality ...
13 hours ago | 5 / 5 (2) | 5
(HealthDay)—Animals make great companions for senior citizens, but elderly people who always drive with a pet in the car are far more likely to crash than those who never drive with a pet, researchers have ...
5 hours ago | not rated yet | 0
Heart failure accelerates the aging process and brings on early andropausal syndrome (AS), according to research presented today at the Heart Failure Congress 2013. AS, also referred to as male 'menopause', was four times ...
13 hours ago | not rated yet | 1
Mortality and length of stay are highest in heart failure patients admitted in January, on Friday, and overnight, according to research presented today at the Heart Failure Congress 2013. The analysis of nearly 1 million ...
13 hours ago | not rated yet | 0
(AP)—Department of Justice lawyers have again asked a federal appeals court in New York to delay lifting age restrictions and prescription requirements on an emergency contraceptive popularly known as the morning-after ...
13 hours ago | not rated yet | 0