New radar better treats mobile tumors
A cancer forms and the battle begins. However, when the tumor floats freely, the disease claims an unfair advantage.
Changzhan Gu, a Texas Tech doctoral student from the Department of Electrical and Computer Engineering, has set out to level the playing field. His new radar will help make treatment safer, more effective and more comfortable for the patients with floating tumors. And his work, under the supervision of assistant professor Changzhi Li, already has won awards at two premier conferences.
The project utilizes radar sensor technology for biomedical applications of respiratory gating and tumor tracking, Gu said. It is a brand-new technology to deal with mobile tumors.
Take lung cancer, for example. At approximately 3 million deaths annually, it is one of the most fatal cancers worldwide. If the tumor is floating, it then becomes a moving target. Compound that with a patients breathing and targeted radiation treatments become exponentially more difficult.
The primary device used to provide external beam radiation treatments to a patient is called a linear accelerator (LINAC). This machine delivers high-energy X-rays to the tumor, regardless of its location on the body. Ideal conditions would dictate that the tumor hold still while the concentrated beam is at work. So in the case of a floating tumor, specialists are forced to treat larger areas to compensate for the movement. While effective, it may damage healthy tissue surrounding that tumor.
This video is not supported by your browser at this time.To minimize the damage, specialists use respiration-gated radiation therapy, a promising treatment modality that precisely delivers a prescribed dose of radiation to floating tumors. Respiration-gated radiation therapy is only effective when the tumor is in a predefined gating window. This is accomplished when the LINAC is synced with the patients breathing pattern, so that radiation may be switched on and off as the tumor passes through the beam. The treatment becomes even more efficient when the patient is able to establish a steady rhythm through coached breathing, or verbal cues that let the patient know when to inhale and when to exhale. This reduces the volume of tissue irradiated, so it is safer and results in fewer side effects and complications, which in turn produces better outcomes.
But as impressive as this technology is, it also has its downfalls. For specialists to be able to monitor the patients respiration in real time, they must place infrared markers to signal the machine when to turn on and off.
Internal markers are intrusive and can produce side effects, Gu said. External markers are uncomfortable and lack accuracy.
This video is not supported by your browser at this time.To help combat the discomfort, Gu has developed a non-contact Doppler radar that better measures respiration signals during respiration-gated radiation therapy. Analysis of the measured signal from Gus device has proven to be more sensitive and more accurate, plus it requires no markers and sends the data back to a computer wirelessly. The radar is even sensitive enough to sense a disruption in the normal breathing pattern, such as a cough.
At one milliwatt, the signal is also remarkably low power, Gu said. It is actually less than a cell phone.
This video is not supported by your browser at this time.
This video is not supported by your browser at this time.Gus research papers Doppler Radar Respiration Measurement for Gated Lung Cancer Radiotherapy and Radar Motion Sensing for Accurate Tumor Tracking in Radiation Therapy has won Best Paper Awards at two premier Institute of Electrical and Electronics Engineers conferences. And he has since filed an invention discloser with the Texas Tech University Office of Technology Commercialization of radar sensor for lung cancer treatment and is taking steps toward filing a provisional patent application before the end of the year.
This research is in collaboration with the Texas Tech University Health Sciences Center, Southwest Cancer Center and the Office of Technology Commercialization.
Provided by Texas Tech University
- Some patients cured by outpatient lung cancer treatment Dec 17, 2010 | not rated yet | 0
- Targeting tumors may help stop spread of breast, other cancers Feb 03, 2012 | not rated yet | 0
- New tumor-tracking technique for radiotherapy spares healthy tissue, could improve cancer treatment Feb 01, 2011 | not rated yet | 0
- Proton imaging provides more accuracy, less radiation to pediatric cancer patients Apr 29, 2011 | not rated yet | 0
- Biologically targeted nanoparticles may boost radiation therapy effects Oct 27, 2011 | not rated yet | 0
- Motion perception revisited: High Phi effect challenges established motion perception assumptions Apr 23, 2013 | 3 / 5 (2) | 2
- Anything you can do I can do better: Neuromolecular foundations of the superiority illusion (Update) Apr 02, 2013 | 4.5 / 5 (11) | 5
- The visual system as economist: Neural resource allocation in visual adaptation Mar 30, 2013 | 5 / 5 (2) | 9
- Separate lives: Neuronal and organismal lifespans decoupled Mar 27, 2013 | 4.9 / 5 (8) | 0
- Sizing things up: The evolutionary neurobiology of scale invariance Feb 28, 2013 | 4.8 / 5 (10) | 14
How can there be a term called "intestinal metaplasia" of stomach
7 hours ago Hello everyone, Ok Stomach's normal epithelium is simple columnar, now in intestinal type of adenocarcinoma of stomach it undergoes "intestinal...
Pressure-volume curve: Elastic Recoil Pressure don't make sense
May 18, 2013 From pressure-volume curve of the lung and chest wall (attached photo), I don't understand why would the elastic recoil pressure of the lung is...
If you became brain-dead, would you want them to pull the plug?
May 17, 2013 I'd want the rest of me to stay alive. Sure it's a lousy way to live but it beats being all-the-way dead. Maybe if I make it 20 years they'll...
MRI bill question
May 15, 2013 Dear PFers, The hospital gave us a $12k bill for one MRI (head with contrast). The people I talked to at the hospital tell me that they do not...
Ratio of Hydrogen of Oxygen in Dessicated Animal Protein
May 13, 2013 As an experiment, for the past few months I've been consuming at least one portion of Jell-O or unflavored Knox gelatin per day. I'm 64, in very...
Alcohol and acetaminophen
May 13, 2013 Edit: sorry for the typo in the title , can't edit I looked around on google quite a bit and it's very hard to find precise information on the...
- More from Physics Forums - Medical Sciences
More news stories
Widely available in pharmacies and health stores, phosphatidylserine is a natural food supplement produced from beef, oysters, and soy. Proven to improve cognition and slow memory loss, it's a popular treatment for older ...
Medical research 1 hour ago | 5 / 5 (1) | 0 |
Researchers at Emory University have identified a protein that stimulates a pair of "orphan receptors" found in the brain, solving a long-standing biological puzzle and possibly leading to future treatments for neurological ...
Medical research 2 hours ago | not rated yet | 0 |
Australian scientists have charted the path of insulin action in cells in precise detail like never before. This provides a comprehensive blueprint for understanding what goes wrong in diabetes.
Medical research 2 hours ago | 4.5 / 5 (2) | 0 |
Researchers at the University of Illinois at Chicago College of Medicine will study gender differences in how the heart uses and stores fat—its main energy source—and how changes in fat metabolism play ...
Medical research 5 hours ago | not rated yet | 0
Nearly 20 percent of kidneys that are recovered from deceased donors in the U.S. are refused for transplant due to factors ranging from scarring in small blood vessels of the kidney's filtering units to the organ going too ...
Medical research 21 hours ago | 5 / 5 (2) | 0 |
(Medical Xpress)—Despite spending billions of dollars on research and development, drug companies have been unable to come up with effective treatments for dementia and Alzheimer's Disease (AD). Now, A. ...
33 minutes ago | 4.5 / 5 (2) | 0 |
Children with autism showed significant improvement after six months of simple sensory exercises at home using everyday items such as scents, spoons and sponges, according to UC Irvine neurobiologists.
19 minutes ago | not rated yet | 0 |
An attack on glioblastoma brain tumor cells that uses a modified poliovirus is showing encouraging results in an early study to establish the proper dose level, researchers at Duke Cancer Institute report.
24 minutes ago | not rated yet | 0
Overweight and obese patients are significantly more likely than their normal-weight counterparts to repeatedly switch primary care doctors, a practice that disrupts continuity of care and leads to more emergency room visits, ...
19 minutes ago | not rated yet | 0
Children who are exposed to secondhand smoke in early childhood are more likely to grow up to physically aggressive and antisocial, regardless of whether they were exposed during pregnancy or their parents have a history ...
56 minutes ago | 1 / 5 (1) | 0
(Medical Xpress)—Native peoples in regions where cameras are uncommon sometimes react with caution when their picture is taken. The fear that something must have been stolen from them to create the photo ...
2 hours ago | 3.5 / 5 (2) | 0 |