S.Africa conducts trials for shorter TB treatment

March 30, 2012

South African researchers said Friday they were conducting medical trials to shorten the duration of tuberculosis treatment to make it easier for patients to complete the full regimen.

"Fighting tuberculosis is going to require new strategies. The ongoing trial aimed at reducing the treatment period from six to four months is one of the new strategies of fighting the disease," said Gavin Churchyard, chief executive of Aurum Institute, an independent medical research body.

"South Africa has the highest burden of TB infections (in the world), therefore it is important to position ourselves in the forefront of new research to help stop the disease," he said.

The trials are conducted at the TB Research Centre, based at a public hospital in Tembisa township east of Johannesburg, one of the areas with the highest infection rates.

Aurum has also partnered with the French Sanofi to increase research capacity in various TB initiatives.

"No organisation can work alone to make a meaningful contribution towards eliminating the disease," said Christopher Viehbacher, chief executive of Sanofi.

"The long period of treatment has been identified as one of the reasons for poor adherence, resulting in drug resistant , which are more expensive to treat," he said.

This month, TB Alliance in Washington unveiled plans for the first clinical tests of a new for tuberculosis that could shorten treatment times to four months in both patients with TB and some forms of drug-resistant TB.

Many fail to complete treatment because they cannot tolerate the difficult side effects of the medications or cannot adhere to the long-term treatment, according to the TB Alliance.

This leads to drug resistant forms of the disease, or even extensively known as XDR-TB.

A total of 8.8 million people worldwide fell ill with the contagious lung disease in 2010 and around 1.4 million died, according to the (WHO).

Explore further: Researchers validate preclinical effectiveness of TB drug target

Related Stories

Trial for new drug-resistant TB treatment to begin

March 19, 2012

A global health alliance Monday unveiled plans for the first clinical tests of a new treatment regimen for tuberculosis, including for patients with resistance to existing multidrug programs.

Recommended for you

The 'love hormone' may quiet tinnitus

September 23, 2016

(HealthDay)—People suffering from chronic ringing in the ears—called tinnitus—may find some relief by spraying the hormone oxytocin in their nose, a small initial study by Brazilian researchers suggests.

Bile acid uptake inhibitor prevents NASH / fatty liver in mice

September 21, 2016

Drugs that interfere with bile acid recycling can prevent several aspects of NASH (nonalcoholic steatohepatitis) in mice fed a high-fat diet, scientists from Emory University School of Medicine and Children's Healthcare of ...

New therapeutic target for Crohn's disease

September 20, 2016

Research from the Sanford Burnham Prebys Medical Discovery Institute (SBP) identifies a promising new target for future drugs to treat inflammatory bowel disease (IBD). The study, published today in Cell Reports, also indicates ...

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.