Standardized treatment plans developed for new-onset JIA

July 3, 2012
Standardized treatment plans developed for new-onset JIA
Four standardized consensus treatment plans have been developed for patients with new-onset systemic juvenile idiopathic arthritis, according to research published in the July issue of Arthritis Care & Research.

(HealthDay) -- Four standardized consensus treatment plans (CTPs) have been developed for patients with new-onset systemic juvenile idiopathic arthritis (JIA), according to research published in the July issue of Arthritis Care & Research.

Esi Morgan Dewitt, M.D., of the Cincinnati Children's Hospital Medical Center, and colleagues administered case-based surveys to members of the Childhood and Rheumatology Research Alliance (CARRA) to identify prevailing treatments for new-onset systemic JIA. Follow-up surveys were used to refine the treatment plans and evaluate their clinical acceptability.

Based on the results of the initial survey the researchers identified considerable variability in the current treatment approaches used by clinicians for new-onset systemic JIA. Four different CTPs were developed for physicians to use during the first nine months of therapy. In addition, case definitions and schedules for clinical and laboratory monitoring were developed. The treatment plans, which consisted of glucocorticoid monotherapy or treatment with methotrexate, anakinra, or tocilizumab, with or without glucocorticoids, were approved by more than 78 percent of the CARRA membership.

"In conclusion, four standardized CTPs for new-onset systemic JIA were developed with the goal of reducing variation in care and to ultimately facilitate evaluation of the comparative effectiveness of these treatments," the authors write. "These plans were found to be acceptable to the majority of survey respondents who are members of CARRA."

Several authors disclosed financial ties to the pharmaceutical industry.

Explore further: Study identifies factors linked with better medication response for treatment of juvenile arthritis

More information: Abstract
Full Text (subscription or payment may be required)

Related Stories

Recommended for you

The promise of precision medicine for rheumatoid arthritis

November 21, 2016

In a new study, a Yale-led research team identified the mechanism of a gene that raises the risk of severe rheumatoid arthritis in susceptible individuals. The finding may lead to the development of treatment based on the ...

Back pain link to 24-hour body clock revealed

August 4, 2016

New research by University of Manchester scientists has for the first time shown that our spinal discs have 24-hour body clocks which when they malfunction, can contribute to lower back pain.

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.