Increased stroke risk at 30-days post-CABG versus PCI

Increased stroke risk at 30-days post-CABG versus PCI
The risk of stroke at 30 days is significantly higher in patients who undergo coronary revascularization with coronary artery bypass graft surgery compared to those who undergo percutaneous coronary intervention, according to research published in the Aug. 28 issue of the Journal of the American College of Cardiology.

(HealthDay) -- The risk of stroke at 30 days is significantly higher in patients who undergo coronary revascularization with coronary artery bypass graft (CABG) surgery compared to those who undergo percutaneous coronary intervention (PCI), according to research published in the Aug. 28 issue of the Journal of the American College of Cardiology.

Tullio Palmerini, M.D., from Policlinico S. Orsola in Bologna, Italy, and colleagues conducted a meta-analysis of 19 trials that included 10,944 patients who were randomized to CABG or PCI.

The researchers found the 30-day rate of stroke to be significantly increased after CABG compared with PCI (1.20 versus 0.34 percent; odds ratio [OR], 2.94). After a median follow-up of 12.1 months, the results were similar (1.83 versus 0.99 percent; OR, 1.67). The relative increase in the risk of stroke observed with CABG compared with PCI at either 30 days or midterm follow-up was not affected by the extent of coronary artery disease (single vessel versus multivessel versus left main). When the outcomes of 33,980 patients from 27 observational studies were analyzed, the results were also similar.

"Coronary revascularization by CABG compared with PCI is associated with an increased risk of stroke at 30 days and at the midterm follow-up," the authors write.

Two authors disclosed financial ties to pharmaceutical companies.

More information: Abstract
Full Text

Related Stories

Recommended for you

Cognitive impairment predicts worse outcome in heart failure

date 11 hours ago

Cognitive impairment predicts worse outcome in elderly heart failure patients, reveals research presented today at Heart Failure 2015 by Hiroshi Saito, a physiotherapist at Kameda Medical Centre in Kamogawa, Japan. Patients ...

1950s drug is future heart treatment

date May 22, 2015

Oxford University researchers have found a promising future treatment for heart disease, going back to a drug first developed in 1950.

Time is muscle in acute heart failure

date May 21, 2015

Urgent diagnosis and treatment in acute heart failure has been emphasised for the first time in joint recommendations published today in European Heart Journal.

User comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.