Study: Optimal treatment duration for MRSA-related pneumonia

The national practice guideline for treating MRSA-related pneumonia is seven to 21 days. A Henry Ford Hospital study found that effective treatment can be done in half the time.

Researchers found that 40 percent of patients were treated for eight to 13 days on a therapy of the antibiotics vancomycin or linezolid, and had the highest survival rate.

The Henry Ford study is believed to be the first to evaluate the length of treatment for MRSA-related pneumonia.

The study is being presented Friday at the annual Society of America meeting in San Diego.

"Based on our study, clinicians can effectively treat their patients within eight to 13 days, thus minimizing patients' exposure to antibiotics and their side effects," says Hadeel Zainah, M.D., a second-year Infectious Diseases fellow at Henry Ford and the study's lead author.

MRSA-related pneumonia is a respiratory illness that typically follows a bout of the flu. Symptoms include a cough, sore throat, head ache, shortness of breath, fever and chills.

In the , researchers evaluated the medical charts of 115 patients hospitalized with MRSA pneumonia. Patients received either or linezolid, or both.

Of the 115 patients, 32 died after 28 days. Other findings:

  • 27 percent of patients were treated for 14-20 days.
  • 13.9 percent of patients were treated for more than 20 days.
  • These treatment durations had lower than the eight to 13 days.
Researchers did not evaluate whether the treatment duration affected length of stay or whether one antibiotic fared better than the other.

add to favorites email to friend print save as pdf

Related Stories

Vancomycin is the drug of choice for treating cellulitis

Oct 23, 2010

Patients admitted to the hospital for the common bacterial skin infection cellulitis should be treated as a first line of defense with the potent antibiotic drug vancomycin rather than other antibiotics such as penicillin, ...

MRSA strain linked to high death rates

Nov 01, 2009

A strain of MRSA that causes bloodstream infections is five times more lethal than other strains and has shown to have some resistance to the potent antibiotic drug vancomycin used to treat MRSA, according to a Henry Ford ...

hVISA linked to high mortality: study

Sep 12, 2010

A MRSA infection with a reduced susceptibility to the potent antibiotic drug vancomycin is linked to high mortality, according to a Henry Ford Hospital study.

Studies: Pneumonia is misdiagnosed on patient readmissions

Oct 22, 2010

Patients were misdiagnosed with pneumonia at an alarming rate when they were readmitted to the hospital shortly after a previous hospitalization for the same illness, according to two Henry Ford Hospital companion studies.

Recommended for you

New step towards eradication of H5N1 bird flu

1 hour ago

A University of Adelaide-led project has developed a new test that can distinguish between birds that have been vaccinated against the H5N1 strain of avian influenza virus or "bird flu" with those that have ...

Africans worst responders in Ebola crisis

1 hour ago

The head of Africa's continental body did not get to an Ebola-hit country until last week—months after alarm bells first rang and nearly 5,000 deaths later.

User comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.