Unsuspected PE seldom linked to death in cancer patients
Unsuspected pulmonary embolism is not associated with an increased risk of death in cancer patients when compared to patients without pulmonary embolism, according to research published in the October issue of the Journal of Thrombosis and Haemostasis.
(HealthDay)—Unsuspected pulmonary embolism (UPE) is not associated with an increased risk of death in cancer patients when compared to patients without pulmonary embolism (PE), according to research published in the October issue of the Journal of Thrombosis and Haemostasis.
M. Sahut D'Izarn, M.D., of the Hôpitaux de Paris, and colleagues conducted a retrospective case-control study involving 132 cancer patients without PE and 65 cancer patients with clinically suspected PE to assess the risk of UPE in cancer patients.
The researchers found that, overall, 40.9 percent of UPE patients had symptoms suggestive of PE. Patients with adenocarcinoma, advanced age, recent chemotherapy, performance status greater than 2, and previous venous thromboembolism were more likely to have UPE. Six-month mortality was not statistically significantly different for patients with UPE compared with those without PE. UPE patients were more likely to have central venous catheters and chemotherapy and less likely to have proximal clots than those with clinically suspected PE. Recurrent venous thromboembolism occurred in 6.1 percent of patients with UPE and 7.7 percent of patients with symptomatic PE.
"In conclusion, in the context of a retrospective study, a high proportion of patients with UPE have respiratory symptoms preceding the diagnosis of PE. This may prompt the attention of the oncologist when a patient at risk for UPE complains of dyspnea or chest pain," the authors write. "The increased mortality rate of patients with UPE seems to be mainly related to their underlying condition and, especially, poor performance status rather than to UPE itself."
One author disclosed financial ties to the pharmaceutical industry.
More information: Abstract
Full Text (subscription or payment may be required)
Copyright © 2012 HealthDay. All rights reserved.
- Unsuspected PE does not up mortality risk in cancer patients Aug 06, 2012 | not rated yet | 0
- Patients with inflammatory bowel disease appear to be at increased risk for post-operative DVT, PE Oct 17, 2011 | not rated yet | 0
- ACP recommends new approach to prevent venous thromboembolism in hospitalized patients Oct 31, 2011 | not rated yet | 0
- CT angiography may be unnecessary in patients with suspected pulmonary embolism Jun 15, 2010 | not rated yet | 0
- Practice patterns in the diagnosis of pulmonary embolism vary, study suggests Mar 22, 2010 | not rated yet | 0
- Motion perception revisited: High Phi effect challenges established motion perception assumptions Apr 23, 2013 | 3 / 5 (2) | 2
- Anything you can do I can do better: Neuromolecular foundations of the superiority illusion (Update) Apr 02, 2013 | 4.5 / 5 (11) | 5
- The visual system as economist: Neural resource allocation in visual adaptation Mar 30, 2013 | 5 / 5 (2) | 9
- Separate lives: Neuronal and organismal lifespans decoupled Mar 27, 2013 | 4.9 / 5 (8) | 0
- Sizing things up: The evolutionary neurobiology of scale invariance Feb 28, 2013 | 4.8 / 5 (10) | 14
Pressure-volume curve: Elastic Recoil Pressure don't make sense
May 18, 2013 From pressure-volume curve of the lung and chest wall (attached photo), I don't understand why would the elastic recoil pressure of the lung is...
If you became brain-dead, would you want them to pull the plug?
May 17, 2013 I'd want the rest of me to stay alive. Sure it's a lousy way to live but it beats being all-the-way dead. Maybe if I make it 20 years they'll...
MRI bill question
May 15, 2013 Dear PFers, The hospital gave us a $12k bill for one MRI (head with contrast). The people I talked to at the hospital tell me that they do not...
Ratio of Hydrogen of Oxygen in Dessicated Animal Protein
May 13, 2013 As an experiment, for the past few months I've been consuming at least one portion of Jell-O or unflavored Knox gelatin per day. I'm 64, in very...
Alcohol and acetaminophen
May 13, 2013 Edit: sorry for the typo in the title , can't edit I looked around on google quite a bit and it's very hard to find precise information on the...
Marie Curie's leukemia
May 13, 2013 Does anyone know what might be the cause of Marie Curie's cancer
- More from Physics Forums - Medical Sciences
More news stories
Older prostate cancer patients with other underlying health conditions should think twice before committing to surgery or radiation therapy for their cancer, according to a multicenter study led by researchers in the UCLA ...
Cancer 7 hours ago | not rated yet | 0 |
Intensity-modulated radiation therapy has become the most commonly used type of radiation in prostate cancer, but research from the University of North Carolina suggests that the therapy may not be more effective than older, ...
Cancer 9 hours ago | not rated yet | 0
New research suggests that a compound abundant in the Mediterranean diet takes away cancer cells' "superpower" to escape death. By altering a very specific step in gene regulation, this compound essentially re-educates cancer ...
Cancer 9 hours ago | 4.8 / 5 (8) | 2 |
(HealthDay)—For young adults needing either a chest or abdominopelvic computed tomography (CT), the short-term risk of death from underlying morbidity is greater than the long-term risk of radiation-induced ...
Cancer 10 hours ago | not rated yet | 0
In a new study described in the journal Oncogene, researchers reveal how a key player in cell growth, immunity and the inflammatory response can be transformed into a primary contributor to tumor growth.
Cancer 16 hours ago | not rated yet | 0 |
Early-life exposure to traffic-related air pollution was significantly associated with higher hyperactivity scores at age 7, according to new research from the University of Cincinnati (UC) and Cincinnati Children's Hospital ...
1 hour ago | not rated yet | 0 |
Bacteria resistant to the antibiotic colistin are also commonly resistant to antimicrobial substances made by the human body, according to a study in mBio, the online open-access journal of the American Society for Microb ...
1 hour ago | not rated yet | 0
(Medical Xpress)—A research team, led by Jeremy Barr, a biology post-doctoral fellow, unveils a new immune system that protects humans and animals from infection.
6 hours ago | 4.5 / 5 (11) | 1 |
Researchers have pinpointed a catalytic trigger for the onset of Alzheimer's disease – when the fundamental structure of a protein molecule changes to cause a chain reaction that leads to the death of neurons ...
10 hours ago | 5 / 5 (3) | 0 |
Salamanders' immune systems are key to their remarkable ability to regrow limbs, and could also underpin their ability to regenerate spinal cords, brain tissue and even parts of their hearts, scientists have ...
10 hours ago | 5 / 5 (4) | 2 |
Turns out, that old "practice makes perfect" adage may be overblown. New research led by Michigan State University's Zach Hambrick finds that a copious amount of practice is not enough to explain why people ...
7 hours ago | 3.1 / 5 (9) | 0 |