Case study IDs B. miyamotoi as cause of meningoencephalitis

Case study IDs <i>B. miyamotoi</i> as cause of meningoencephalitis
The spirochete Borrelia miyamotoi may be an underrecognized cause of meningoencephalitis, according to a case study published in the Jan. 17 issue of the New England Journal of Medicine.

(HealthDay)—The spirochete, Borrelia miyamotoi, may be an underrecognized cause of meningoencephalitis, according to a case study published in the Jan. 17 issue of the New England Journal of Medicine.

Joseph L. Gugliotta, M.D., of the Robert Wood Johnson Medical School in New Brunswick, N.J., and colleagues report the case of a B. miyamotoi infection-associated meningoencephalitis which developed in an immunocompromised patient.

According to the report, an 80-year-old woman who lived on a farm in New Jersey, who had been treated twice for and was immunocompromised due to treatment for non-Hodgkin's lymphoma, developed progressive over a four-month period. She was admitted to the hospital and diagnosed with meningoencephalitis. Although Koch's postulates were not met, the woman's illness was posited to be caused by infection with the spirochete B. miyamotoi as the organism was directly detected in cerebrospinal fluid using both microscopy and assay. Following treatment with antibiotics, the patient's physical and mental conditions improved.

"In older persons, changes in mental status are often attributed to dementia or the aging process. Exposure of such persons to diverse microbial agents, including those thought to be nonpathogenic, such as B. miyamotoi, may represent possibilities for pathologic processes to occur," the authors write. "Immunocompromise in older patients should always prompt a more rigorous laboratory analysis, because such persons may serve as sentinels for poorly recognized or novel pathogens."

More information: Full Text (subscription or payment may be required)
Letter to the Editor

add to favorites email to friend print save as pdf

Related Stories

New tick-borne disease discovered

Sep 20, 2011

(Medical Xpress) -- Yale School of Public Health researchers in collaboration with Russian scientists have discovered a new tick-borne bacterium that might be causing disease in the United States and elsewhere. ...

Deer ticks carry yet another bacterial threat

Jan 16, 2013

(HealthDay)—People who go outdoors in several regions of the United States may have something else to worry about. Scientists report that there's another troublesome germ hiding in the deer tick that already ...

Study examines the effect of epilepsy on the aging

Apr 16, 2008

An article published in the May 2008 issue of Epilepsia calls attention to the lack of knowledge regarding cognitive aging in chronic epilepsy patients. For persons with chronic epilepsy, little is known about the impact ...

Good long-term prognosis after West Nile virus infection

Aug 18, 2008

The long-term prognosis of patients infected with West Nile virus is good, according to a new study appearing in the August 19, 2008, issue of Annals of Internal Medicine, the American College of Physicians' flagship journa ...

Recommended for you

Overwhelmed west Africa escalates Ebola response

37 minutes ago

West Africa intensified its response to the deadly Ebola epidemic on Sunday, with Sierra Leone uncovering scores of dead bodies during a 72-hour shutdown and Liberia announcing 1,000 hospital beds.

Sierra Leone reaches final day of Ebola lockdown

4 hours ago

Frustrated residents complained of food shortages in some neighborhoods of Sierra Leone's capital on Sunday as the country reached the third and final day of a sweeping, unprecedented lockdown designed to ...

Sierra Leone faces criticism over Ebola shutdown

Sep 20, 2014

Sierra Leone began the second day of a 72-hour nationwide shutdown aimed at containing the spread of the deadly Ebola virus on Saturday amid criticism that the action was a poorly planned publicity stunt.

Presence of peers ups health workers' hand hygiene

Sep 19, 2014

(HealthDay)—The presence of other health care workers improves hand hygiene adherence, according to a study published in the October issue of Infection Control and Hospital Epidemiology.

User comments