Poor arthritis outcome risk up in overweight black women

January 23, 2013
Poor arthritis outcome risk up in overweight black women
Overweight African-American women with or at risk of knee osteoarthritis are at higher risk than overweight white women of poor functional outcomes, according to a study published in the January issue of Arthritis Care & Research.

(HealthDay)—Overweight African-American women with or at risk of knee osteoarthritis are at higher risk than overweight white women of poor functional outcomes, according to a study published in the January issue of Arthritis Care & Research.

Carmelita J. Colbert, M.D., from Northwestern University in Chicago, and colleagues analyzed whether excess body weight was associated with poorer four-year functional outcomes (as determined by the Western Ontario and McMaster Universities Index function, 20-meter walk and chair stand performance) in African-Americans compared with whites in 3,695 patients (16.1 percent African-American) with or at higher risk for .

The researchers found that a higher body mass index and large waist circumference correlated with poorer outcomes. Among women with either feature, African-American women had a higher risk of poor outcomes, after adjusting for age, education, and income. The findings were potentially explained by income, comorbidity, depressive symptoms, pain, and disease severity. For men, findings were less consistent and were potentially explained by age and knee pain.

"Among Osteoarthritis Initiative women with excess body weight, African-Americans are at greater risk than whites for poor four-year outcome," Colbert and colleagues conclude. "Modifiable factors that may help to explain these findings in the Osteoarthritis Initiative include comorbidity, depressive symptoms, and knee pain."

The study was partially funded by Merck, Novartis, GlaxoSmithKline, and Pfizer as part of the Osteoarthritis Initiative, a public-private partnership.

Explore further: Putting your foot in it: but shoes can make a difference

More information: Abstract
Full Text

Related Stories

4.5 million Americans living with total knee replacement

February 10, 2012

New research presented at the 2012 Annual Meeting of the American Academy of Orthopaedic Surgeons (AAOS) found that more than 4.5 million Americans are living with a total knee replacement (TKR), as the number of TKR surgeries ...

Recommended for you

Team finds gene that confirms existence of psoriatic arthritis

February 5, 2015

PsA is a common form of inflammatory form of arthritis causing pain and stiffness in joints and tendons that can lead to joint damage. Nearly all patients with PsA also have skin psoriasis and, in many cases, the skin disease ...

Blocking one receptor could halt rheumatoid arthritis

September 10, 2014

Researchers at the University of Illinois at Chicago College of Medicine have shown for the first time how the activation of a receptor provokes the inflammation and bone degradation of rheumatoid arthritis—and that activation ...

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.