Study points to risk factors of mesh-related complications in prolapse surgery patients

Younger age, less prominent prolapse and concomitant hysterectomies are associated with a higher risk of peri-operative and mesh-related complications after prolapse repair with trocar-guided transvaginal mesh, according to a study presented by a Russian group at the 28th Annual EAU Congress.

This retrospective multicenter study, which included 677 from 6 centres, aimed to evaluate intraoperative, early postoperative and mesh-related complications for surgical management of female pelvic organ prolapse (POP) with application of trocar guided transvaginal synthetic mesh.

In the course of the study the patients underwent POP surgery from 2006 to 2010. The patients were operated for symptomatic genital prolapse POP-Q stage 2 to 4. Patients were systematically seen within 1 and 3 months and then evaluated again during the study via phone interview and those who reported complaints during interview were evaluated in the office settings. with normal distribution were analysed via Student test; whereas Fisher exact test was used for the non-parametric criteria.

Mean age of the patients was 60 +- 12,7 years. At the time of study 586 patients from 677 were available for phone interview (86.5%). Intra-operative, early postoperative and mesh-related complications were noted in 17.3%of patients (152/677). Fifteen patients (2.2%) developed bleeding during the surgery over 500 cc; significant pelvic and vaginal hematomas were found in 37 cases (5.5%); perineal hematomas were noticed in 17 patients (2.5%).

There were two cases of urethral injuries (0.3%); 11 patients had bladder injury during surgery (1.6%); rectal damage in 5 cases (0.7%) and one case of ureteral (0.2%).

Mesh related complications were limited to 32 cases of mesh (4.8%), 2 cases of vaginal synechias (0.3%), one protrusion of mesh into the bladder (0.15%), two cases of vesicovaginal fistula with mesh (0.3%), 7 cases of mesh shrinkage and 16 patients complaints to dyspareunia and pain (2.4%). Pelvic abscess was found in 4 cases (0.6%).

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