Low vitamin D linked with lower kidney function after transplantation

Vitamin D deficiency may decrease kidney function in transplant recipients, according to a study appearing in an upcoming issue of the Journal of the American Society of Nephrology (JASN). The finding suggests that vitamin D supplementation may help improve the health of kidney transplant recipients.

is prevalent in patients with . It's not clear how this affects patients after they receive a kidney transplant. To investigate, Frank Bienaimé, MD (Université Paris Descartes and INSERM and Assistance Publique Hopitaux de Paris) and his colleagues studied a group of 634 kidney recipients who underwent transplantation between January 2005 and June 2010.

The researchers found that low vitamin D levels measured at three months after transplantation were linked with lower kidney function and increased kidney scarring at 12 months post-transplant. Other hormones involved with mineral metabolism were not predictors of kidney function or scarring after one year.

"This result suggests that maintaining vitamin D concentration within the normal range would prevent renal function deterioration after renal transplantation," said Dr. Bienaimé. "Vitamin D supplementation, a simple and inexpensive treatment, may improve transplantation outcomes." He encouraged the design of to evaluate the potential of vitamin D supplements to maintain kidney function following transplantation.

More information: The article, entitled "Vitamin D Status and Outcomes After Renal Transplantation," will appear online on March 28, 2013, doi: 10.1681/ASN.2012060614

add to favorites email to friend print save as pdf

Related Stories

Drug fails to help kidney transplant recipients

Jan 10, 2013

A drug that protects the kidneys of patients with chronic kidney disease does not seem to provide the same benefit to kidney transplant recipients, according to a study appearing in an upcoming issue of the Journal of th ...

Time to stop giving toxic drugs to kidney transplant patients?

Sep 22, 2011

Patients who receive kidney transplants must take lifelong medications that, while preventing organ rejection, can also compromise other aspects of health. Immunosuppresive drugs called calcineurin inhibitors protect transplanted ...

Recommended for you

New MCAT shifts focus, will include humanities

16 hours ago

(HealthDay)—The Medical College Admission Test (MCAT) has been revised, and the latest changes, including more humanities such as social sciences, are due to be implemented next April, according to a report ...

Using feminist theory to understand male rape

Oct 20, 2014

Decades of feminist research have framed rape and sexual assault as a 'women's issue', leaving little room for the experiences of male victims. But a new study published in the Journal of Gender Studies suggests that feminist ...

Simulation-based training improves endoscopy execution

Oct 18, 2014

(HealthDay)—Simulation-based training (SBT) improves clinicians' performance of gastrointestinal endoscopy in both test settings and clinical practice, according to research published in the October issue ...

User comments