4.4 mmol/L is optimal fasting glucose cutoff for GDM screening

4.4 mmol/L is optimal fasting glucose cutoff for GDM screening
A fasting plasma glucose value of 4.4 mmol/L is the optimal cut point for determining which pregnant Chinese women need a 75-g 2-h oral glucose tolerance test offered at 24 to 28 weeks' gestation, according to a study published online March 27 in Diabetes Care.

(HealthDay)—A fasting plasma glucose value of 4.4 mmol/L is the optimal cut point for determining which pregnant Chinese women need a 75-g 2-h oral glucose tolerance test offered at 24 to 28 weeks' gestation, according to a study published online March 27 in Diabetes Care.

Wei-Wei Zhu, M.D., from Peking University First Hospital in China, and colleagues analyzed the medical records and results of a 75-g 2-h (OGTT) from 24,854 pregnant women without known pre-gestational diabetes mellitus (pre-GDM).

The researchers found that a fasting plasma glucose cutoff value of 5.1 mmol/L identified 3,149 pregnant women (12.1 percent) with GDM. A fasting plasma glucose cutoff value of 4.4 mmol/L ruled out GDM in 15,369 women (38.2 percent) women, which would miss 12.2 percent of patients with mild GDM. The is 0.322, and the negative predictive value is 0.928.

"Fasting at 24 to 28 weeks' gestation could be used as a screening test to identify GDM patients in low-resource regions," the authors write.

More information: Abstract
Full Text (subscription or payment may be required)

add to favorites email to friend print save as pdf

Related Stories

Gestational diabetes, obesity impact pregnancy outcomes

Mar 02, 2012

(HealthDay) -- Women with gestational diabetes mellitus (GDM) who are obese have significantly higher odds of adverse pregnancy outcomes, according to findings from the multinational Hyperglycemia and Adverse ...

Key variables examined in gestational diabetes advance

Mar 18, 2013

(HealthDay)—For women with gestational diabetes mellitus (GDM), clinical and genetic factors including higher pre-pregnancy body mass index are associated with development of type 2 diabetes mellitus (T2DM), ...

Adoption of new screening guidelines ups GDM diagnosis

Jul 20, 2012

(HealthDay) -- Implementation of the International Association of Diabetes in Pregnancy Study Group (IADPSG) recommendations for gestational diabetes mellitus (GDM) screening in Israel would increase GDM diagnoses ...

Recommended for you

Mechanism behind age-dependent diabetes discovered

9 hours ago

Ageing of insulin-secreting cells is coupled to a progressive decline in signal transduction and insulin release, according to a recent study by researchers at Karolinska Institutet in Sweden. The finding, ...

Pre-diabetes, diabetes rates fuel national health crisis

Sep 16, 2014

Americans are getting fatter, and older. These converging trends are putting the USA on the path to an alarming health crisis: Nearly half of adults have either pre-diabetes or diabetes, raising their risk of heart attacks, ...

User comments