4.4 mmol/L is optimal fasting glucose cutoff for GDM screening

4.4 mmol/L is optimal fasting glucose cutoff for GDM screening
A fasting plasma glucose value of 4.4 mmol/L is the optimal cut point for determining which pregnant Chinese women need a 75-g 2-h oral glucose tolerance test offered at 24 to 28 weeks' gestation, according to a study published online March 27 in Diabetes Care.

(HealthDay)—A fasting plasma glucose value of 4.4 mmol/L is the optimal cut point for determining which pregnant Chinese women need a 75-g 2-h oral glucose tolerance test offered at 24 to 28 weeks' gestation, according to a study published online March 27 in Diabetes Care.

Wei-Wei Zhu, M.D., from Peking University First Hospital in China, and colleagues analyzed the medical records and results of a 75-g 2-h (OGTT) from 24,854 pregnant women without known pre-gestational diabetes mellitus (pre-GDM).

The researchers found that a fasting plasma glucose cutoff value of 5.1 mmol/L identified 3,149 pregnant women (12.1 percent) with GDM. A fasting plasma glucose cutoff value of 4.4 mmol/L ruled out GDM in 15,369 women (38.2 percent) women, which would miss 12.2 percent of patients with mild GDM. The is 0.322, and the negative predictive value is 0.928.

"Fasting at 24 to 28 weeks' gestation could be used as a screening test to identify GDM patients in low-resource regions," the authors write.

More information: Abstract
Full Text (subscription or payment may be required)

add to favorites email to friend print save as pdf

Related Stories

Gestational diabetes, obesity impact pregnancy outcomes

Mar 02, 2012

(HealthDay) -- Women with gestational diabetes mellitus (GDM) who are obese have significantly higher odds of adverse pregnancy outcomes, according to findings from the multinational Hyperglycemia and Adverse ...

Key variables examined in gestational diabetes advance

Mar 18, 2013

(HealthDay)—For women with gestational diabetes mellitus (GDM), clinical and genetic factors including higher pre-pregnancy body mass index are associated with development of type 2 diabetes mellitus (T2DM), ...

Adoption of new screening guidelines ups GDM diagnosis

Jul 20, 2012

(HealthDay) -- Implementation of the International Association of Diabetes in Pregnancy Study Group (IADPSG) recommendations for gestational diabetes mellitus (GDM) screening in Israel would increase GDM diagnoses ...

Recommended for you

Economic burden of prediabetes up 74 percent over five years

Nov 20, 2014

The economic burden of diabetes in America continues to climb, exceeding more than $322 billion in excess medical costs and lost productivity in 2012, or more than $1,000 for every American, according to a study being published ...

Gynoid fat resists metabolic risks of obesity

Nov 19, 2014

(HealthDay)—The differences in the developmental profiles of upper-body and lower-body fat depots may explain their opposing associations with obesity-related metabolic disease, according to research published ...

Treating diabetes one meal at a time

Nov 19, 2014

Recent estimates project that as many as one in three American adults will have diabetes in 2050. The American Diabetes Association observes November as American Diabetes Month, and this year's theme is America ...

User comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.