Depression risk drops from pre- to post-final period

Depression risk drops from pre- to post-final period
There is a higher risk of depression before and a lower risk after the final menstrual period, according to a study published online Nov. 13 in JAMA Psychiatry.

(HealthDay)—There is a higher risk of depression before and a lower risk after the final menstrual period (FMP), according to a study published online Nov. 13 in JAMA Psychiatry.

Ellen W. Freeman, Ph.D., from the University of Pennsylvania School of Medicine in Philadelphia, and colleagues examined within-woman changes in depressive symptoms during a 14-year period around menopause in a population-based sample of 203 late-reproductive-age who were premenopausal at baseline and reached natural menopause.

The researchers observed a decrease in the prevalence of high scores on the Center for Epidemiologic Studies Depression Scale, from 10 years before to eight years after the FMP, with an approximate decrease of 15 percent of baseline per year. In the years before and after the FMP, the risk of depressive symptoms was higher and lower, respectively, relative to the FMP. Compared to women with no history of , for women with a history of depression, the likelihood of depressive symptoms was 13-fold higher overall and eight-fold higher after menopause. The risk of depressive symptoms decreased after the FMP for women who first experienced depressive symptoms approaching menopause, with a significantly reduced risk in the second year after .

"The FMP was pivotal in the overall pattern of decreasing in midlife women, with higher risk before and lower risk after the FMP," the authors write.

Two authors disclosed financial ties to the pharmaceutical and biotechnology industries.

More information: Abstract
Full Text (subscription or payment may be required)

add to favorites email to friend print save as pdf

Related Stories

Depressive symptoms tied to doubled risk for Crohn's

Jan 16, 2013

(HealthDay)—Depressive symptoms are associated with a two-fold increase in risk of Crohn's disease (CD) but not ulcerative colitis (UC), according to research published in the January issue of Clinical Ga ...

Study explores bipolar in postpartum period

Nov 08, 2013

Researchers have long connected mood disorders and pregnancy. But a study coming out of Western is boiling down some of the specifics, suggesting women who suffered from depression prior to pregnancy should be monitored for ...

Diet is associated with the risk of depression

Sep 16, 2013

A healthy diet may reduce the risk of severe depression, according to a prospective follow-up study of more than 2,000 men conducted at the University of Eastern Finland. In addition, weight loss in the context of a lifestyle ...

Recommended for you

Brains transform remote threats into anxiety

Nov 21, 2014

Modern life can feel defined by low-level anxiety swirling through society. Continual reports about terrorism and war. A struggle to stay on top of family finances and hold onto jobs. An onslaught of news ...

Mental disorders due to permanent stress

Nov 21, 2014

Activated through permanent stress, immune cells will have a damaging effect on and cause changes to the brain. This may result in mental disorders. The effects of permanent stress on the immune system are studied by the ...

Could there be a bright side to depression?

Nov 21, 2014

(Medical Xpress)—A group of researchers studying the roots of depression has developed a test that leads them closer to the idea that depression may actually be an adaptation meant to help people cope with ...

User comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.