Availability of transcatheter repair of aortic stenosis benefits patients

January 30, 2014

The introduction of minimally invasive transcatheter aortic valve replacement (TAVR) for treatment of aortic stenos not only has increased the number of patients eligible for aortic valve replacement (AVR), but also has led to a decrease in patient mortality, according to a study released today at the 50th Annual Meeting of The Society of Thoracic Surgeons. These results suggest that patients fare better when multiple treatment options are available.

Using data from the STS Adult Cardiac Surgery Database and the STS/ACC Transcatheter Valve Therapy (TVT) Registry, J. Matthew Brennan, MD, MPH, from Duke University Medical Center in Durham, NC, and colleagues evaluated the overall volume and outcomes from aortic valve interventions at participating U.S. hospitals from 2008 to 2012. TAVR became commercially available in the United States in 2012.

The study is the first to examine volume and outcomes at a national level.

"Early in the TAVR experience, there was concern that the availability of transcatheter procedures would lead to an abrupt reduction in the volume of surgical valve replacements," said Dr. Brennan. "Our findings confirm what other surgeons have observed—implementation of a TAVR program likely will broaden the surgical referral base and increase the volume of considered for treatment."

Across the study period, the total annual volume of aortic valve interventions increased from 34,699 to 43,282. In addition, the researchers found that overall mortality associated with AVR decreased, even in high-risk cases (8.9% in 2011 vs. 7.0% in 2012).

"In the initial U.S. experience, early outcomes following replacement have improved with the availability of TAVR technology," said Dr. Brennan. "When surgeons have multiple treatment options, more patients will benefit. We expect this trend to continue as both device technology and patient selection continue to evolve."

The TVT Registry currently has more than 10,000 patient records and enrollment is on track to double that number in the next year. The large number of patient records allows for the development of reliable benchmarks for centers to reference in comparing their local results against risk-adjusted national standards. Ultimately this will translate into improved patient selection and optimal patient care.

Explore further: Quality of life benefits of transcatheter aortic valve replacement differ by access site

Related Stories

Recommended for you

Female smokers face greatest risk for brain bleeds

July 21, 2016

Bleeding inside the lining of the brain (subarachnoid hemorrhage) is significantly more common among smokers, especially female smokers, than among people who do not smoke, according to new research in the American Heart ...

Global study shows stroke largely preventable

July 15, 2016

Ten risk factors that can be modified are responsible for nine of 10 strokes worldwide, but the ranking of those factors vary regionally, says a study led by researchers of the Population Health Research Institute (PHRI) ...

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.