Intensive lifestyle reverses glucose abnormalities in youth

February 1, 2014
Intensive lifestyle reverses glucose abnormalities in youth

(HealthDay)—An intensive lifestyle intervention can reverse early glucose abnormalities in obese youth, according to a study published in the February issue of Diabetes Care.

Mary Savoye, R.D., C.D.E., from Yale University in New Haven, Conn., and colleagues randomized obese adolescents (10 to 16 years old; Tanner stage >2) with elevated (OGTT) two-hour blood glucose (130 to 199 mg/dL) to either the Bright Bodies (BB) Healthy Lifestyle Program, including exercise and nutrition/behavior modification, or standard clinical care (CC). At baseline and at six months, OGTTs as well as cardiovascular and anthropometric assessments were conducted.

The researchers found that BB participants had greater reductions in two-hour glucose compared to CC participants (P = 0.005). Furthermore, there was greater conversion to <130 mg/dL two-hour glucose in the BB group than the CC group (P = 0.003).

"Compared with standard of care, the Yale BB Program is a more effective means of reducing the risk of type 2 diabetes in obese adolescents with elevated two-hour glucose levels," Savoye and colleagues conclude.

Explore further: Metformin treatment beneficial for obese children, teens

More information: Abstract
Full Text (subscription or payment may be required)

Related Stories

Metformin treatment beneficial for obese children, teens

December 21, 2012

(HealthDay)—Obese children and adolescents treated with twice-daily metformin have significantly improved body mass index standard deviation scores (BMI-SDS), fasting glucose, and other metabolic risk factors, according ...

Sucralose affects response to oral glucose load in obese

July 2, 2013

(HealthDay)—For obese adults who do not use non-nutritive sweetener (NNS), sucralose affects the glycemic and insulin responses to an oral glucose load, according to a study published online April 30 in Diabetes Care.

Cinnamon cuts blood glucose levels in diabetes patients

September 16, 2013

(HealthDay)—Consumption of cinnamon is associated with favorable reductions in plasma glucose and lipid levels, according to research published in the September/October issue of the Annals of Family Medicine.

Artificial sweeteners produce no glucagon response

January 14, 2014

(HealthDay)—Artificial sweeteners do not produce any changes in glucose metabolism compared to a glass of water, according to a letter published in the December issue of Diabetes Care.

Recommended for you

Gut bacteria imbalance increases diabetes risk

July 13, 2016

Currently, scientists think the major contributors to insulin resistance are excess weight and physical inactivity, yet ground-breaking new research by an EU funded European-Chinese team of investigators called MetaHit have ...

Which diabetes drug is best?

July 19, 2016

(HealthDay)—No single drug to treat type 2 diabetes stands out from the pack when it comes to reducing the risks of heart disease, stroke or premature death, a new research review finds.

Team explores genetic architecture of type 2 diabetes

July 11, 2016

New research from a large international team of scientists offers a more complete picture of the genes responsible for type 2 diabetes, demonstrating that previously identified common alleles shared by many in the world are ...

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.