High blood pressure increases risk of stroke for atrial fibrillation patients

Poor blood pressure control among patients with atrial fibrillation is associated with a 50-percent increased risk of stroke, according to an analysis presented by Duke Medicine researchers.

The findings, presented in a poster Saturday, March 29, 2014, at the American College of Cardiology meeting in Washington, D.C., suggest that hypertension should be carefully monitored and controlled among patients with atrial fibrillation.

Using data from a large clinical trial called ARISTOTLE, the Duke researchers analyzed more than 18,000 patients with atrial fibrillation to understand how affects their health.

Strokes were more common in atrial fibrillation patients who had a history of high blood pressure, or who had high blood pressure at the start of the study. A significant increase in the risk of stroke was also seen in patients who had high blood pressure measurements at any point during the study.

"This study is unique in that we looked at patients with atrial fibrillation who had a history of high blood pressure, patients who had high at the start of the study, and blood pressure control during the course of the study," said lead author Meena Rao, M.D., MPH, research fellow at the Duke Clinical Research Institute.

"We found that having high blood pressure at any point during the trial led to an increased risk of stroke by approximately 50 percent in patients with atrial fibrillation," Rao said. "This highlights the importance of in addition to anticoagulation to reduce the risk of stroke in patients with atrial fibrillation."

The ARISTOTLE trial, led by DCRI researchers, studied two anticoagulant drugs for treating , an that can result in the formation of blood clots and cause stroke.

Related Stories

Study discovers new way to prevent some strokes

date Feb 18, 2014

Larry Ambrose woke up one night, wandered into his kitchen but couldn't completely read the time on his microwave. A few days later when he noticed his blood pressure was unusually high, he went to the hospital ...

Recommended for you

A-fib recurrence common five years after ablation

date 18 hours ago

(HealthDay)—Most patients with atrial fibrillation (AF) and systolic heart failure who undergo ablation have AF recurrence at five years, according to a study published in the April issue of the Journal of ...

Applied physics helps decipher the causes of sudden death

date 22 hours ago

Sudden cardiac death accounts for approximately 10% of natural deaths, most of which are due to ventricular fibrillation. Each year, it causes 300,000 deaths in the United States and 20,000 in Spain. Researchers have demonstrated ...

Cognitive problems are common after cardiac arrest

date 22 hours ago

Half of all patients who survive a cardiac arrest experience problems with cognitive functions such as memory and attention. This has been shown by a major international study led from Lund University. Surprisingly, however, ...

User comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.