Nocturnal respiratory rate predicts cardiac risk after MI

March 10, 2014
Nocturnal respiratory rate predicts cardiac risk after MI

(HealthDay)—Among survivors of acute myocardial infarction (MI), nocturnal respiratory rate (NRR) is significantly associated with cardiac mortality, particularly non-sudden cardiac death, according to research published online March 5 in the Journal of the American College of Cardiology.

Michael Dommasch, M.D., of the Medizinische Klinik der Technischen Universität München, and colleagues applied an algorithm to data from Holter electrocardiographic recordings for 1,538 MI survivors to determine NRR. The researchers examined the association between NRR and cardiac death.

The researchers found that NRR was 18.6 per minute or greater in 384 patients and less than 18.6 per minute in 1,154 patients; five-year in these groups was 13.7 and 3.3 percent, respectively (P < 0.001). NRR of 18.6 per minute or greater was significantly associated with non- (hazard ratio, 4.56; 95 percent confidence interval, 2.21 to 9.43; P < 0.001). Among 155 patients with left ventricular ejection fraction of 35 percent or less, NRR of 18.6 per minute or greater was significantly associated with cardiac mortality (P < 0.001) and non-sudden cardiac death (P = 0.009), but not sudden cardiac death (P = 0.595).

"Among patients with left ventricular ejection fraction ≤35 percent, i.e., (ICD) candidates, increased NRR identifies a group of patients with frequent non-sudden cardiac death, i.e., a mode of death likely not ICD preventable," the authors write. "Independent validation of this new risk stratification approach is necessary before it can be incorporated into clinical decision-making."

More information: Full Text (subscription or payment may be required)

Related Stories

QRS width on ECG linked to sudden cardiac arrest in CAD

April 20, 2012

(HealthDay) -- For patients with coronary artery disease (CAD), QRS width on electrocardiogram and echocardiographic evidence of heart failure are associated with out-of-hospital sudden cardiac arrest (SCA), regardless of ...

Potentially pathological ECG patterns prevalent in young

March 6, 2014

(HealthDay)—More than 20 percent of young non-athletes have electrocardiogram (ECG) patterns that can be considered potentially pathological based on the 2010 European Society of Cardiology position paper, according to ...

Recommended for you

Heart attack treatment hypothesis 'busted'

July 6, 2015

Researchers have long had reason to hope that blocking the flow of calcium into the mitochondria of heart and brain cells could be one way to prevent damage caused by heart attacks and strokes. But in a study of mice engineered ...

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.