Nocturnal respiratory rate predicts cardiac risk after MI

Nocturnal respiratory rate predicts cardiac risk after MI

(HealthDay)—Among survivors of acute myocardial infarction (MI), nocturnal respiratory rate (NRR) is significantly associated with cardiac mortality, particularly non-sudden cardiac death, according to research published online March 5 in the Journal of the American College of Cardiology.

Michael Dommasch, M.D., of the Medizinische Klinik der Technischen Universität München, and colleagues applied an algorithm to data from Holter electrocardiographic recordings for 1,538 MI survivors to determine NRR. The researchers examined the association between NRR and cardiac death.

The researchers found that NRR was 18.6 per minute or greater in 384 patients and less than 18.6 per minute in 1,154 patients; five-year in these groups was 13.7 and 3.3 percent, respectively (P < 0.001). NRR of 18.6 per minute or greater was significantly associated with non- (hazard ratio, 4.56; 95 percent confidence interval, 2.21 to 9.43; P < 0.001). Among 155 patients with left ventricular ejection fraction of 35 percent or less, NRR of 18.6 per minute or greater was significantly associated with cardiac mortality (P < 0.001) and non-sudden cardiac death (P = 0.009), but not sudden cardiac death (P = 0.595).

"Among patients with left ventricular ejection fraction ≤35 percent, i.e., (ICD) candidates, increased NRR identifies a group of patients with frequent non-sudden cardiac death, i.e., a mode of death likely not ICD preventable," the authors write. "Independent validation of this new risk stratification approach is necessary before it can be incorporated into clinical decision-making."

More information: Full Text (subscription or payment may be required)

Related Stories

Potentially pathological ECG patterns prevalent in young

date Mar 06, 2014

(HealthDay)—More than 20 percent of young non-athletes have electrocardiogram (ECG) patterns that can be considered potentially pathological based on the 2010 European Society of Cardiology position paper, ...

QRS width on ECG linked to sudden cardiac arrest in CAD

date Apr 20, 2012

(HealthDay) -- For patients with coronary artery disease (CAD), QRS width on electrocardiogram and echocardiographic evidence of heart failure are associated with out-of-hospital sudden cardiac arrest (SCA), ...

Recommended for you

Cognitive impairment predicts worse outcome in heart failure

date May 24, 2015

Cognitive impairment predicts worse outcome in elderly heart failure patients, reveals research presented today at Heart Failure 2015 by Hiroshi Saito, a physiotherapist at Kameda Medical Centre in Kamogawa, Japan. Patients ...

1950s drug is future heart treatment

date May 22, 2015

Oxford University researchers have found a promising future treatment for heart disease, going back to a drug first developed in 1950.

Time is muscle in acute heart failure

date May 21, 2015

Urgent diagnosis and treatment in acute heart failure has been emphasised for the first time in joint recommendations published today in European Heart Journal.

User comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.