Serum potassium levels linked to long-term mortality post-MI

April 14, 2014
Serum potassium levels linked to long-term mortality post-MI

(HealthDay)—For patients with acute myocardial infarction (AMI), serum potassium levels are associated with long-term mortality risk, according to a study published in the April 15 issue of The American Journal of Cardiology.

Joon Seok Choi, M.D., from the Chonnam National University Medical School in Gwangju, South Korea, and colleagues examined the impact of serum potassium levels on long-term mortality in a cohort of 1,924 diagnosed with AMI. The average serum potassium levels were measured throughout hospitalization; patients were classified into five groups according to mean serum potassium: <3.5, 3.5 to <4.0, 4.0 to <4.5, 4.5 to <5.0, and ≥5 mEq/L.

The researchers found that patients with potassium levels of 3.5 to <4.0 mEq/L had lowest long-term mortality. Higher mortality was seen for patients with potassium levels <3.5 or ≥4.5 mEq/L. In a multivariate analysis, compared to patients with potassium levels of 3.5 to <4.0 mEg/L, mortality risk was significantly increased for serum potassium levels of 4.5 to <5.0 mEq/L and ≥5.0 mEq/L (hazard ratio, 1.71 [95 percent confidence interval, 1.04 to 2.81] and 4.78 [95 percent confidence interval, 2.14 to 10.69], respectively). An increased risk was also seen for patients with potassium levels of <3.5 mEq/L (hazard ratio, 1.55; 95 percent confidence interval, 0.94 to 2.56). No correlation was seen between serum potassium levels and the occurrence of ventricular arrhythmias.

"The results of the current analysis suggest that there is a need for change in our current concepts of the ideal serum potassium levels in patients with AMI," the authors write.

More information: Abstract
Full Text (subscription or payment may be required)

Related Stories

AMI up with stress-induced hyperglycemia after hip fx

July 15, 2013

(HealthDay)—For patients after hip fracture, stress-induced hyperglycemia is associated with an increased risk of acute myocardial infarction (AMI), according to a study published online July 11 in Diabetes Care.

Post-discharge deaths drop in young acute MI patients

March 31, 2014

(HealthDay)—In the most recent decade, compared with earlier decades, post-discharge death rates have dropped for young adults hospitalized for acute myocardial infarction (AMI), according to research published in the April ...

Recommended for you

Heart attack treatment hypothesis 'busted'

July 6, 2015

Researchers have long had reason to hope that blocking the flow of calcium into the mitochondria of heart and brain cells could be one way to prevent damage caused by heart attacks and strokes. But in a study of mice engineered ...

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.