Serum potassium levels linked to long-term mortality post-MI

Serum potassium levels linked to long-term mortality post-MI

(HealthDay)—For patients with acute myocardial infarction (AMI), serum potassium levels are associated with long-term mortality risk, according to a study published in the April 15 issue of The American Journal of Cardiology.

Joon Seok Choi, M.D., from the Chonnam National University Medical School in Gwangju, South Korea, and colleagues examined the impact of serum potassium levels on long-term mortality in a cohort of 1,924 diagnosed with AMI. The average serum potassium levels were measured throughout hospitalization; patients were classified into five groups according to mean serum potassium: <3.5, 3.5 to <4.0, 4.0 to <4.5, 4.5 to <5.0, and ≥5 mEq/L.

The researchers found that patients with potassium levels of 3.5 to <4.0 mEq/L had lowest long-term mortality. Higher mortality was seen for patients with potassium levels <3.5 or ≥4.5 mEq/L. In a multivariate analysis, compared to patients with potassium levels of 3.5 to <4.0 mEg/L, mortality risk was significantly increased for serum potassium levels of 4.5 to <5.0 mEq/L and ≥5.0 mEq/L (hazard ratio, 1.71 [95 percent confidence interval, 1.04 to 2.81] and 4.78 [95 percent confidence interval, 2.14 to 10.69], respectively). An increased risk was also seen for patients with potassium levels of <3.5 mEq/L (hazard ratio, 1.55; 95 percent confidence interval, 0.94 to 2.56). No correlation was seen between serum potassium levels and the occurrence of ventricular arrhythmias.

"The results of the current analysis suggest that there is a need for change in our current concepts of the ideal serum potassium levels in patients with AMI," the authors write.

More information: Abstract
Full Text (subscription or payment may be required)

Related Stories

Post-discharge deaths drop in young acute MI patients

date Mar 31, 2014

(HealthDay)—In the most recent decade, compared with earlier decades, post-discharge death rates have dropped for young adults hospitalized for acute myocardial infarction (AMI), according to research published ...

Recommended for you

Catheterization increasing for seniors with STEMI

date 18 hours ago

(HealthDay)—From 1999 to 2009 there was a decrease in the proportion of older adults with ST-segment elevation acute myocardial infarction (STEMI) who did not undergo cardiac catheterization, according ...

Race influences warfarin dose, study says

date May 29, 2015

A new report demonstrates that clinical and genetic factors affecting dose requirements for warfarin vary by race. The study, published online today in Blood, the Journal of the American Society of Hematology (ASH), propose ...

Even moderate BMI reduction could ease A-fib burden

date May 29, 2015

(HealthDay)—Incremental increases in body mass index (BMI) are associated with excess risk of incident, postoperative, and post-ablation atrial fibrillation (AF), according to a review published online ...

Personalized saline may provide solution to heart death

date May 29, 2015

Saline solution is a staple of every hospital. No matter the ailment, doctors have known for more than a century that saline is key to keeping patients hydrated and maintaining their blood pressure levels. ...

User comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.