Glutamate imaging better than MR spectroscopy in first three hours after ischemic stroke

Glutamate imaging reveals ischemic lesions in the first 3 hours after stroke that are not distinguishable in T1-weighted and T2-weighted imaging.

Researchers using chemical exchange saturation transfer (CEST), an emerging MRI technology, have found that using glutamate with CEST shows in vivo. The finding has the potential to speed diagnosis—and, therefore, treatment—in the critical first hours after a stroke.

"I have been interested in glutamate imaging since its inception," said researcher Zhuozhi Dai of Second Affiliated Hospital of Shantou University Medical College, Shantou, China. "Being able to evaluate glutamate in the brain could be of great benefit in the clinical setting."

More information: Dr. Dai presented the study on Monday, May 5 at the 2014 ARRS Annual Meeting in San Diego, CA.

Related Stories

Peritoneal dialysis as an intervention for stroke patients

date Sep 03, 2013

Ischemic stroke is characterized by an interruption of the blood supply to the brain, which can lead to brain damage and even death. Excess amounts of the excitatory neurotransmitter glutamate are released during stroke events ...

Imaging the brain's energy usage

date Jan 22, 2014

A team of researchers led by Kai-Hsiang Chuang of the A*STAR Singapore Bioimaging Consortium has developed a new imaging technique to measure the rate at which the brain consumes glucose, without using radioactively ...

Recommended for you

European court to rule on right-to-die case

date 22 hours ago

Europe's human rights court will on June 5 rule on whether a man in a vegetative state can be taken off life support, a case that has ignited a fierce euthanasia debate in France, a spokesman said Thursday.

Mechanical ventilation associated with long-term disability

date May 19, 2015

Critically ill patients who have been mechanically ventilated for more than seven days are at greatly increased risk for functional impairment and mortality at one year following discharge from the intensive care unit (ICU), ...

User comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.