Agency for Science, Technology and Research (A*STAR), Singapore
How connections in the brain must change to form memories could help to develop artificial cognitive computers
Exactly how memories are stored and accessed in the brain is unclear. Neuroscientists, however, do know that a primitive structure buried in the center of the brain, called the hippocampus, is a pivotal region ...
Neuroscience
Nov 07, 2012 |
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The screening of thousands of fluorescent molecules has revealed a specific label for neural stem cells
Neural stem cells are the precursors of cells in the nervous system. As well as being crucial for early development, they are present throughout life, contributing to flexibility and repair of the nervous ...
Medical research
Oct 24, 2012 |
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Recently uncovered human counterparts to a subset of mouse immune cells may enable better vaccination strategies
Mice have made an immeasurable contribution to medicine and our overall understanding of human disease. This animal model is not without its limitations, however, and scientists are continually learning about ...
Medical research
Oct 24, 2012 |
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Scientists identify mutation that causes skin hyperproliferation
Scientists have identified a mutation in a gene that causes patches of very thick skin to appear on the palms and soles of affected people. This skin disorder is related, albeit in a much milder form, to ...
Genetics
Oct 18, 2012 |
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Inappropriate activation of an immune signaling pathway during infection leaves the body vulnerable to sepsis
The inflammatory response is a double-edged sword—it enables the body to mount a vigorous defense against infection, but can also inflict serious physiological damage if allowed to rampage uncontrolled. ...
Immunology
Sep 26, 2012 |
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Jump-starting cheaper cancer vaccines
Dendritic cells (DCs)—workhorses of the immune system—derived from human embryonic stem cells (hESCs) may provide an economical way of generating off-the-shelf therapeutic vaccines against cancers, according ...
Immunology
Sep 26, 2012 |
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Lipids produced within the thymus give immune cells the initial boost they need to fight off infection
Semi-invariant natural killer T (iNKT) cells wage war against infectious threats, attacking microbial cells and generating signals that enable other immune cells also to respond aggressively. iNKT cells initially ...
Immunology
Sep 12, 2012 |
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Bonanza of genomic sequence data gives researchers valuable new insights into a poorly understood cancer
Stomach cancer doesn't get the same publicity as lung or breast cancer, but it is a health threat to be taken very seriously. "Gastric cancer is the second leading cause of worldwide cancer mortality, with ...
Genetics
Sep 12, 2012 |
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Cancer research: Stealth techniques being developed to delay tumor growth
The way in which cancer can spread silently and unnoticed in the body—with symptoms in some cases remaining latent for months, years, or even decades—is often noted as its most deadly feature. Researchers ...
Cancer
Sep 12, 2012 |
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Earlier treatment for young patients with chronic hepatitis B more effective in clearing virus
Scientists from A*STAR's Singapore Institute for Clinical Sciences (SICS), together with clinical collaborators from London , discovered for the first time that children and young patients with chronic Hepatitis B Virus infection ...
Diseases, Conditions, Syndromes
Sep 06, 2012 |
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Potential drug for treating deadly brain cancer
(Medical Xpress)—A*STAR scientists have identified a biomarker of the most lethal form of brain tumours in adults − glioblastoma multiforme. The scientists found that by targeting this biomarker and depleting ...
Cancer
Sep 04, 2012 |
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Singapore scientists find genes associated with glaucoma
Singapore scientists have identified three new genes associated with Primary Angle Closure Glaucoma (PACG), a leading cause of blindness in Chinese people. PACG affects 15 million people worldwide, 80% of whom live in Asia.
Genetics
Sep 03, 2012 |
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New research sheds light on the molecular mechanisms by which a virus contributes to cancer
Hepatocellular carcinoma (HCC) is the third leading cause of cancer deaths worldwide and is associated with exposure to hepatitis B virus (HBV). Patients carrying the virus have a 100-fold greater risk of ...
Cancer
Aug 29, 2012 |
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Langerhans cells migrate to their final destination in multiple waves at different stages of embryonic development
As our primary interface with the outside world, the skin needs to be able to protect itself against infectious threats. Specialized cells known as Langerhans cells (LCs) (see image) are an essential component ...
Medical research
Aug 29, 2012 |
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Genetic disease linked to protein build-up
Mutations of the gene Lmna previously thought to be directly responsible for a group of laminopathies—serious developmental conditions including premature aging and a form of muscular dystrophy—in fact ...
Medical research
Aug 29, 2012 |
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