American Association for Cancer Research
Diverse genetic alterations found in triple-negative breast cancers after neoadjuvant chemotherapy
Many different genetic alterations were detected in tumor cells left behind after patients with triple-negative breast cancer were treated with chemotherapy prior to surgery (neoadjuvant chemotherapy), according to data presented ...
Cancer
Dec 07, 2012 |
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Potential new technique for anticancer radiotherapy could provide alternative to brachytherapy
A promising new approach to treating solid tumors with radiation was highly efficacious and minimally toxic to healthy tissue in a mouse model of cancer, according to data published in Cancer Research, a journal of the Am ...
Cancer
Nov 15, 2012 |
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PI3-kinase and PARP inhibitor combo may offer new treatment option for triple-neg breast cancers
The simultaneous inhibition of two separate and seemingly unrelated pathways could potentially provide an effective treatment for women with triple-negative breast cancer, according to results of two studies published in ...
Cancer
Nov 12, 2012 |
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New mechanism of action for PARP inhibitors discovered
New understanding of how drugs called PARP inhibitors, which have already shown promise for the treatment of women with familial breast and ovarian cancers linked to BRCA mutations, exert their anticancer effects has led ...
Cancer
Nov 09, 2012 |
4 / 5 (1) |
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Inflammation marker linked to increased risk for death from cancer in Korean men
Measuring blood levels of high-sensitive C-reactive protein, an important marker of inflammation, in apparently cancer-free men could potentially help identify those at increased risk for death from cancer, in particular ...
Cancer
Nov 07, 2012 |
5 / 5 (1) |
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Ethnic disparities in breast cancer survival remain despite socioeconomic similarities
Disparities in survival after breast cancer persisted across racial/ethnic groups even after researchers adjusted for multiple demographics, such as patients' education and the socioeconomic status of the neighborhood in ...
Cancer
Oct 30, 2012 |
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Participation in clinical trials high among gay, lesbian and bisexual cancer survivors
Cancer survivors who self-identified as being lesbian, gay or bisexual were more than twice as likely as heterosexual cancer survivors to have participated in cancer clinical trials, according to data from a small study presented ...
Cancer
Oct 30, 2012 |
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Socioeconomic disadvantage linked to breast cancer tumor disparity
Racial and ethnic disparities in breast tumor aggressiveness might be explained by social factors that influence the developing tumor and place those in disadvantaged groups at higher risk for aggressive breast cancer, according ...
Cancer
Oct 30, 2012 |
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Biomarkers of behavior, therapeutic targets for adult B-acute lymphoblastic leukemia identified
New insight into the aggressive behavior of certain adult B-acute lymphoblastic leukemias has provided researchers with a potential new prognostic biomarker and a promising new therapeutic target.
Cancer
Oct 29, 2012 |
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Hispanic breast cancer survivors' perception of health affected by English-language proficiency
Hispanic breast cancer survivors who considered their English-language proficiency as limited were less likely to rate their own health as good, very good or excellent, according to data presented at the Fifth AACR Conference ...
Cancer
Oct 29, 2012 |
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Genetic research may advance understanding of ethnic differences in breast cancer
For the first time, researchers have provided a direct comparison of gene expression profiles from African-American and East African breast tissue samples, according to results presented at the Fifth AACR Conference on The ...
Cancer
Oct 29, 2012 |
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Genes involved in vitamin D generation and destruction may influence colorectal cancer risk in African-Americans
African-Americans are more likely than non-Hispanic whites to have and die from colorectal cancer. Changes in the DNA sequence of genes that affect how the body makes and destroys vitamin D modify the risk for colorectal ...
Cancer
Oct 29, 2012 |
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Minorities most likely to have aggressive tumors, less likely to get radiation
Women with aggressive breast cancer were more likely to receive adjuvant chemotherapy, but at the expense of completing locoregional radiation therapy, according to recently presented data. This was especially true in minorities, ...
Cancer
Oct 29, 2012 |
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Language, immigration status of hispanic caregivers impacted care of children with cancer
Language barriers and the immigration status of caregivers appear to impact the care of Hispanic children with cancer and affect the experience of the families within the medical system, according to data presented at the ...
Cancer
Oct 29, 2012 |
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Women in less affluent areas of Chicago less likely to reside near mammography facility
Women in socioeconomically disadvantaged and less affluent areas of Chicago were less likely to live near a mammography facility with various aspects of care compared with women in less socioeconomically disadvantaged and ...
Cancer
Oct 29, 2012 |
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