Cell Transplantation Center of Excellence for Aging and Brain Repair
The mission of the Center of Excellence for Aging and Brain Repair is to develop new therapeutic strategies to promote repair and regeneration of aging and diseased brain. Building on a foundation of excellence in basic and clinical research, we focus on translating innovative ideas into industrial partnerships, educational and clinical services to address key needs of the community and those suffering from brain injury and disease.
Environmental enrichment important factor impacting cell transplantation and brain repair
A team of Korean researchers investigated whether "environmental enrichment" can improve the neurobehavioral function of six week-old mice after transplantation of adipose-derived stem cells (ASCs) to treat hypoxic-ischemic ...
Medical research
Mar 27, 2013 |
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Third-party blood stem cell transplantation as a factor to impact on poor graft function
When a research team in China evaluated the efficacy and safety of using mesenchymal stem cells (MSCs) expanded from the bone marrow of non-self-donors to treat patients experiencing poor graft function (PGF) after receiving ...
Medical research
Mar 18, 2013 |
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Impact of stem cell transplantation location in brain a crucial factor for cell survival
Researchers at the Johns Hopkins University in Baltimore, Md., and the Mossakowski Medical Research Centre in Warsaw, Poland, have found that nonself-donated cells (allografts) better survive implantation into the brains ...
Medical research
Feb 13, 2013 |
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Stem cell source an important factor, impacting ability to treat myocardial infarction
When a research team from Denmark and Sweden compared the therapeutic capabilities of adipose-derived stem cells (ASCs) versus bone marrow-derived stem cells (BMSCs) obtained from a single 84 year-old male donor with ischemic ...
Medical research
Feb 13, 2013 |
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New study investigates fate and function of cells transplanted to the CNS
When different types of cells are transplanted with the intent of having them aid in repairing central nervous system (CNS) trauma, what is the fate and function of those cells? A Belgian research team carried out research ...
Medical research
Dec 20, 2012 |
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Transplanted genetically-modified adipose cells offer potential therapy for liver diseases
Using mesenchymal stromal cells derived from adipose (fat) tissues, genetically modified to express a bioluminescent marker, researchers in Italy have tracked cells after transplantation. The cells were followed from their ...
Medical research
Dec 20, 2012 |
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Study suggests different organ-derived stem cell injections improve heart function
A study published in the current issue of Cell Transplantation (21:8), now freely available on-line, has found that when mesenchymal cells derived from skeletal muscle (SM-MSCs) or adipose tissue (ADSCs) were injected into t ...
Cardiology
Nov 27, 2012 |
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Researchers report islet cell advancement increases impact on transplantation
A study published in the current issue of Cell Transplantation (21:8), now freely available on-line, reports that a team of researchers in South Korea have successfully engineered islet cell clusters (ICCs) that will improv ...
Medical research
Nov 27, 2012 |
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Studies investigate oxygen's impact as a factor in transplantation
Two studies published in the current issue of Cell Transplantation (21:7), now freely available on-line, investigate the role of oxygen in cell transplantation.
Medical research
Nov 15, 2012 |
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MRI images transplanted islet cells with help of positively charged nanoparticles
In a study to investigate the detection by MRI of six kinds of positively-charged magnetic iron oxide nanoparticles designed to help monitor transplanted islet cells, a team of Japanese researchers found that the charged ...
Medical research
Oct 01, 2012 |
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Therapeutic time window important factor for cord blood cell transplantation after stoke
A research team from Germany has found that optimal benefit and functional improvement for ischemic stroke results when human umbilical cord blood mononuclear cells (hUCB MNCs) are transplanted into rat stroke models within ...
Medical research
Oct 01, 2012 |
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Cryopreservation of induced pluripotent stem cells improved the most by one product
In a study to determine the best cryopreservation (freezing) solution to maintain induced pluripotent stem (iPS) cells, a team of researchers from Japan compared 12 kinds of commercially prepared and readily available cryopreservation ...
Medical research
Sep 25, 2012 |
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Mouse pancreatic stem cells successfully differentiate into insulin producing cells
In a study to investigate how transplanted islet cells can differentiate and mature into insulin-producing pancreatic cells, a team of Japanese researchers found that using a specific set of transcription factors (proteins ...
Medical research
Sep 25, 2012 |
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Therapeutic impact of cell transplantation aided by magnetic factor
Two studies in the current issue of Cell Transplantation (21:6), now freely available on-line, demonstrate how the use of magnetic particles are a factor that can positively impact on the targeted delivery of transplante ...
Medical research
Sep 24, 2012 |
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Blood vessel forming potential of stem cells from human placenta and umbilical cord blood
A study comparing whether endothelial colony-forming cells (ECFCs) derived from human placenta or those derived from human umbilical cord blood are more proliferative and better for forming new blood vessels has found that ...
Medical research
Jul 19, 2012 |
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