Children's Hospital of Philadelphia

Viral protein silences immune alarm signals

Viruses must avoid a host's immune system to establish successful infections—and scientists have discovered another tool that viruses use to frustrate host defenses. Researchers from The Children's Hospital of Philadelphia ...

Jun 29, 2016
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New gene variants found in childhood body mass index

An international team of scientists has identified novel gene locations associated with childhood body mass index (BMI)—an important measurement related to childhood obesity. The meta-analysis, covering over 47,000 children, ...

Mar 10, 2016
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Change in a single DNA base drives a childhood cancer

Pediatric oncology researchers have pinpointed a crucial change in a single DNA base that both predisposes children to an aggressive form of the childhood cancer neuroblastoma and makes the disease progress once tumors form.

Nov 11, 2015
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Cancer-driving signals cause high-risk neuroblastoma

Researchers have discovered details of the abnormal molecular signals and biological events that drive a high-risk form of the childhood cancer neuroblastoma. They aim to use these findings to develop more effective targeted ...

Oct 15, 2015
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