Medical research
Scientists grow human esophagus in lab
Scientists working to bioengineer the entire human gastrointestinal system in a laboratory now report using pluripotent stem cells to grow human esophageal organoids.
Sep 20, 2018
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469
Cincinnati Children's Hospital Medical Center
Immunology
Detecting epigenetic signature may help people stay ahead of inflammatory bowel disease
With an estimated 1.6 million people in the U.S. dealing with inflammatory bowel disease (IBD), physicians can have a hard time telling which newly diagnosed patients have a high risk of severe inflammation or what therapies ...
Sep 20, 2018
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1
Health
Overall well-being of a population associated with less per capita medicare spending
A new study in JAMA Network Open finds that the overall well-being of a population on a county level is associated with lower healthcare spending for each Medicare fee-for-service beneficiary.
Sep 14, 2018
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Medical research
Timing may be everything when taking meds
Using new bioinformatics tools to analyze thousands of human tissue samples, researchers at Cincinnati Children's Hospital Medical Center created a new database of daily rhythms in human gene activity—including many genes ...
Sep 12, 2018
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42
Medical research
Scientists block RNA silencing protein in liver to prevent obesity and diabetes in mice
Obesity and its related ailments like type 2 diabetes and fatty liver disease pose a major global health burden, but researchers report in Nature Communications that blocking an RNA-silencing protein in the livers of mice ...
Sep 10, 2018
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322
Oncology & Cancer
Scientists close in on mystery surrounding dangerous blood syndromes
Scientists may be on the road to solving the mystery of a group of mostly incurable blood diseases called myelodysplastic syndromes (MDS), which cause people to have immature, malfunctioning bone marrow cells that fuel a ...
Aug 23, 2018
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13
Cardiology
Taking a pill can effectively treat brutal lung disease
Researchers report in Nature Communications they figured out why air sacs in the lungs clog up with a thick substance called surfactant in a brutal disease called Pulmonary Alveolar Proteinosis (PAP), and they show taking ...
Aug 7, 2018
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109
Oncology & Cancer
Preclinical study points to potential treatment targets for aggressive pediatric leukemia
When a dangerous defect on chromosome 11q23 disrupts the genetic programming of blood cells, it causes an aggressive and deadly blood cancer called acute myeloid leukemia (AML). With a dismal survival rate of 20-40 percent ...
Jul 11, 2018
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21
Genetics
Scientists learn more about how gene linked to autism affects brain
New preclinical research shows a gene already linked to a subset of people with autism spectrum disorder is critical to healthy neuronal connections in the developing brain, and its loss can harm those connections to help ...
Jun 18, 2018
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66
Oncology & Cancer
Study suggests well-known growth suppressor actually fuels lethal brain cancers
Scientists report finding a potentially promising treatment target for aggressive and deadly high-grade brain cancers like glioblastoma. But they also say the current lack of a drug that hits the molecular target keeps it ...
Jun 18, 2018
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