Cincinnati Children's Hospital Medical Center

Experimental molecular therapy crosses blood-brain barrier to treat neurological disease

Researchers have overcome a major challenge to treating brain diseases by engineering an experimental molecular therapy that crosses the blood-brain barrier to reverse neurological lysosomal storage disease in mice.

Medical research created Feb 04, 2013 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Newly identified protein function protects cells during injury

Scientists have discovered a new function for a protein that protects cells during injury and could eventually translate into treatment for conditions ranging from cardiovascular disease to Alzheimer's.

Medical research created Jun 07, 2012 | popularity not rated yet | comments 0 | with audio podcast

Researchers find possible therapeutic strategy to combat premature birth

Scientists who developed a novel mouse model mimicking human preterm labor have described a molecular signaling pathway underlying preterm birth and targeted it to stop the problem.

Medical research created Oct 24, 2011 | popularity not rated yet | comments 0 | with audio podcast

Study raises concerns that teen athletes continue to play with concussion symptoms

Despite knowing the risk of serious injury from playing football with a concussion, half of high school football players would continue to play if they had a headache stemming from an injury sustained on the field.

Pediatrics created May 06, 2013 | popularity 4 / 5 (1) | comments 0

Study finds saliva testing predicts aggression in boys

(Medical Xpress)—A new study indicates that a simple saliva test could be an effective tool in predicting violent behavior.

Psychology & Psychiatry created Mar 26, 2013 | popularity 3.7 / 5 (7) | comments 0 | with audio podcast

Study suggests improved treatment alternative for lymphoid leukemia

Discovering what they call the "Achilles' heel" for lymphoid leukemia, an international research team has tested a possible alternative treatment that eradicated the disease in mouse models.

Cancer created Feb 11, 2013 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Researchers use new molecular inhibitors to successfully hit difficult cancer target

Early laboratory tests are the first to successfully use an experimental molecular therapy to block a hard-to-target part of a protein complex linked to several types of invasive cancer.

Cancer created Feb 05, 2013 | popularity 5 / 5 (1) | comments 0 | with audio podcast

30 percent of teen girls report meeting offline with someone they met online

A new study highlights the risk that female teenagers face when they go online – a risk heightened for teen girls who have been victims of abuse or neglect.

Pediatrics created Jan 14, 2013 | popularity not rated yet | comments 0 | with audio podcast

Research identifies targeted molecular therapy for untreatable NF1 tumors

Researchers conducting a preclinical study in mice successfully used targeted molecular therapy to block mostly untreatable nerve tumors that develop in people with the genetic disorder Neurofibromatosis 1 (NF1).

Cancer created Dec 10, 2012 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Drug shrinks brain tumors in children with tuberous sclerosis complex

A drug originally developed to prevent the rejection of transplanted organs has now been shown to dramatically reduce a particular kind of brain tumor in patients with tuberous sclerosis complex (TSC)—a genetic disease ...

Cancer created Nov 13, 2012 | popularity not rated yet | comments 0 | with audio podcast

Child's home address helps predict risk of readmission to hospital

Simply knowing a child's home address and some socioeconomic data can serve as a vital sign – helping hospitals predict which children admitted for asthma treatment are at greater risk for re-hospitalization or additional ...

Health created Oct 18, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Study adds to efforts to find more effective anti-inflammatory drugs

Researchers have discovered a previously unknown function for a protein that could add to the expanding arsenal of potential new drugs for battling inflammation and tissue fibrosis in a number of disease processes.

Inflammatory disorders created Sep 27, 2012 | popularity not rated yet | comments 0 | with audio podcast

Pregnancy generates maternal immune-suppressive cells that protect the fetus

A new study published online in the journal Nature suggests it might be possible to develop vaccines to prevent premature birth and other pregnancy complications. If so, such vaccines would be the first intended to stimul ...

Immunology created Sep 26, 2012 | popularity not rated yet | comments 0 | with audio podcast

Scientists show biological mechanism can trigger epileptic seizures

Scientists have discovered the first direct evidence that a biological mechanism long suspected in epilepsy is capable of triggering the brain seizures – opening the door for studies to seek improved treatments or even ...

Neuroscience created Sep 19, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Study implicates marijuana use in pregnancy problems

New research indicates marijuana-like compounds called endocannabinoids alter genes and biological signals critical to the formation of a normal placenta during pregnancy and may contribute to pregnancy complications like ...

Medical research created Sep 12, 2012 | popularity not rated yet | comments 1 | with audio podcast