Cold Spring Harbor Laboratory
Cold Spring Harbor Laboratory, (CSHL) traces its roots to 1890. It is presently located in Suffolk County, Long Island, New York. The private, not for profit lab scientists from the Carnegie Institution of Department of Genetics have made significant contributions in the study and treatment of genetics and medicine. Recently, The Watson School of Biological Sciences was established which employs 400 scientists. CSHL has an educational and research component. CSHL has eight Nobel Laureates who have been associated with the lab. Many break-through discoveries have been made at CSHL. Among the discoveries is the work by John D. Watson who co-discovered the double helix structure of DNA with Francis Crick. Robert J. Roberts received the Nobel Prize for the co-discovery of introns and RNA splicing. CSHL requires all inquiries from the media and public go through Mr. Tarr, e-mail provided.
Cold Spring Harbor, NY 11724
516-367-8800
Rats take high-speed multisensory snapshots
When animals are on the hunt for food they likely use many senses, and scientists have wondered how the different senses work together. New research from the laboratory of CSHL neuroscientist and Assistant Professor Adam ...
Neuroscience
May 07, 2013 |
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Scientists discover how brain's auditory center transmits information for decisions, actions
When a pedestrian hears the screech of a car's brakes, she has to decide whether, and if so, how, to move in response. Is the action taking place blocks away, or 20 feet to the left?
Neuroscience
May 01, 2013 |
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A novel surface marker helps scientists 'fish out' mammary gland stem cells
Stem cells are different from all other cells in our body because they retain the remarkable genetic plasticity to self-renew indefinitely as well as develop into cell types with more specialized functions. However, this ...
Cancer
Apr 11, 2013 |
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Neuroscientists show 'jumping genes' may contribute to aging-related brain defects
As the body ages, the physical effects are notable; wrinkles in the skin appear, physical exertion becomes harder. But there are also less visible processes going on. Inside aging brains there is another phenomenon at work, ...
Neuroscience
Apr 08, 2013 |
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Do we always make better decisions when we take more time to think?
A study led by Zachary Mainen, Director of the Champalimaud Neuroscience Programme, and published today (March 28) in the scientific journal, Neuron, reports that when rats were challenged with a series of perceptual decisi ...
Neuroscience
Mar 28, 2013 |
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Cancer-promoting protein found to also suppress cell growth
Some cellular proteins have multiple, and occasionally opposing, functions. Professor Adrian Krainer [link: Faculty profile] and colleagues at Cold Spring Harbor Laboratory demonstrate in a paper published online today in ...
Medical research
Mar 07, 2013 |
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Researchers identify new strategy for interfering with potent cancer-causing gene
Acute myeloid leukemia (AML) is an aggressive blood cancer that is currently incurable in 70% of patients. In a bold effort, CSHL scientists are among those identifying and characterizing the molecular mechanisms responsible ...
Cancer
Feb 11, 2013 |
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Neuroscientists pinpoint location of fear memory in amygdala
A rustle of undergrowth in the outback: it's a sound that might make an animal or person stop sharply and be still, in the anticipation of a predator. That "freezing" is part of the fear response, a reaction to a stimulus ...
Neuroscience
Jan 28, 2013 |
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Team finds mechanism of one of the most powerful tumor-suppressor proteins, Chd5
A team of cancer researchers at Cold Spring Harbor Laboratory (CSHL) has solved the mystery of how one of the most powerful of the body's natural tumor-suppressing proteins, called Chd5, exerts its beneficial effects.
Cancer
Jan 10, 2013 |
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Nobel laureate publishes novel hypothesis on curing late-stage cancers
In a new paper he regards "among my most important work since the double helix," Nobelist James Watson sets forth a novel hypothesis regarding the role of oxidants and antioxidants in cancers that are currently incurable, ...
Cancer
Jan 08, 2013 |
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Study solves birth and migration mysteries of cortex's powerful inhibitors, 'chandelier' cells
A team at CSHL for the 1st time reveals the birth timing and embryonic origin of a critical class of inhibitory brain cells called chandelier cells, tracing the specific paths they take during early development into the cerebral ...
Neuroscience
Nov 22, 2012 |
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Team uses antisense technology that exploits gene splicing mechanism to kill cancer cells
Cancer cells grow fast. That's an essential characteristic of what makes them cancer cells. They've crashed through all the cell-cycle checkpoints and are continuously growing and dividing, far outstripping our normal cells. ...
Cancer
Oct 31, 2012 |
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Neuroscientists propose revolutionary DNA-based approach to map wiring of whole brain
A team of neuroscientists has proposed a new and potentially revolutionary way of obtaining a neuronal connectivity map (the "connectome") of the whole brain of the mouse. The details are set forth in an essay published October ...
Neuroscience
Oct 23, 2012 |
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Scientists reverse Alzheimer's-like memory loss in animal models by blocking EGFR signaling
A team of neuroscientists and chemists from the U.S. and China today publish research suggesting that a class of currently used anti-cancer drugs as well as several previously untested synthetic compounds show effectiveness ...
Alzheimer's disease & dementia
Sep 24, 2012 |
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Research identifies protein that regulates key 'fate' decision in cortical progenitor cells
Researchers at Cold Spring Harbor Laboratory (CSHL) have solved an important piece of one of neuroscience's outstanding puzzles: how progenitor cells in the developing mammalian brain reproduce themselves while also giving ...
Neuroscience
Sep 21, 2012 |
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