Federation of American Societies for Experimental Biology

Oncology & Cancer

New strategy to reduce cancer drug's cardiotoxic effects

Doxorubicin (Doxo) is a widely used chemotherapeutic drug for cancer, though it can have toxic effects on the heart. A recent animal study published in The FASEB Journal investigated whether the cardioregulatory protein chromogranin ...

Cardiology

Study suggests novel biomarker for predicting AFib progression

A human study published in The FASEB Journal suggests a novel type of biomarker to predict the progression of atrial fibrillation (AF), the most common form of irregular heart rhythm. Despite inconsistent evidence to date, ...

Neuroscience

GI neuroimmune disruption contributes to Gulf War Illness

Many Persian Gulf War veterans experience Gulf War Illness (GWI), a chronic condition with symptoms ranging from gastrointestinal to neurological. While exposure to the anti-nerve gas pyridostigmine bromide (PB) is linked ...

Medical research

Magnetic fields enhance bone remodeling

Since the creation of 3-D-printed (3DP) porous titanium scaffolds in 2016, the scientific community has been exploring ways to improve their ability to stimulate osteogenesis, or bone remodeling. A recent study published ...

Oncology & Cancer

Molecular mechanisms behind AICAr drug; impact on ALL

AICAr (5-amino-4-imidazolecarboxamide riboside, also called Acadesine) has been found to inhibit cell proliferation and has cytotoxic potential for childhood acute lymphoblastic leukemia (ALL) cells. Much of the drug's cytotoxic ...

Obstetrics & gynaecology

Alternations in gut microbiota in pregnancy and lactation

Recent studies have shown that maternal gut microbiota in humans primes the offspring's immune and metabolic development during pregnancy and lactation. Due to environmental factors that are impractical to control in human ...

Diseases, Conditions, Syndromes

Bile salt receptor linked to replication and repression of HBV virus

Despite an efficient and well-tolerated vaccine, hepatitis B (HBV) remains a major public health problem, with more than 250 million people at high risk of developing liver cirrhosis and cancer as a result. HBV treatment ...

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