Garvan Institute of Medical Research

The Garvan Institute of Medical Research was founded in 1963 by the Sisters of Charity. Initially a research department of St Vincent's Hospital in Sydney, it is now one of Australia's largest medical research institutions with approximately 500 scientists, students and support staff. Funds for its establishment were provided by a hospital appeal. Helen Mills, the largest donor, asked for the centre to be named after her father, the late James Patrick Garvan (1843-1896), a distinguished New South Wales parliamentarian and business leader. Garvan's research programs are based around the major diseases in today's society: cancer, diabetes, osteoporosis, Alzheimer's, Parkinson's; as well as eating disorders, and autoimmune and inflammatory conditions such as rheumatoid arthritis and asthma. It specialises in genetic and molecular technologies, and emphasises collaborative research. The current director is John Mattick.

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Unsuspected aspect of immune regulation revealed

Until now, the immune cells known as 'B cells' have been thought to specialise only in the production of antibodies. A discovery by Garvan immunologists shows they also have a role to play in regulating another ...

Jul 01, 2014
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Slowing down the immune system when in overdrive

Many people suffer from chronic inflammation because their immune systems overreact to 'self' tissue. Sydney scientists believe that a small molecule known as Interleukin 21 is a promising therapeutic target in such cases.

Feb 10, 2014
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Molecular interplay explains many immunodeficiencies

Australian scientists have described an exquisitely balanced interplay of four molecules that trigger and govern antibody production in immune cells. As well as being an important basic science discovery, it helps explain ...

Nov 11, 2013
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Rapid reversal of diabetes after gastric banding surgery

Clinical researchers from Sydney's Garvan Institute of Medical Research and St. Vincent's Hospital have shown that a form of weight loss surgery, known as 'gastric banding', brings about reversal of diabetes in some patients, ...

Oct 15, 2013
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New hope for hormone resistant breast cancer

A new finding provides fresh hope for the millions of women worldwide with oestrogen receptor positive breast cancer. Australian scientists have shown that a specific change, which occurs when tumours become resistant to ...

Jul 22, 2013
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