Genetics
A natural history of neurons: Diverse mutations reveal lineage of brain cells
Walt Whitman's famous line, "I am large, I contain multitudes," has gained a new level of biological relevance.
Oct 1, 2015
5
124
Harvard Medical School
Medical research
Stem cells repair lung damage after flu infection
Guided by insights into how mice recover after H1N1 flu, researchers at Harvard Medical School and Brigham and Women's Hospital, together with researchers at A*STAR of Singapore, have cloned three distinct stem cells from ...
Oct 27, 2011
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1
Neuroscience
Researchers uncover diverse subtypes of serotonin-producing neurons
It used to be enough to call a serotonergic neuron a serotonergic neuron.
Nov 6, 2015
1
174
Neuroscience
New X-ray microscopy technique enables comprehensive imaging of dense neural circuits
One of the grand quests in neuroscience is to build a precise map of the brain, charting all its neurons and the connections between them. Such a wiring diagram, called a connectome, promises to help shed light on how a collection ...
Sep 14, 2020
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396
Medical research
'Lifespan machine' probes cause of aging: Findings suggest that aging has no single mechanism
Aging is one of the most mysterious processes in biology. We don't know, scientifically speaking, what exactly it is. We do know for sure when it ends, but to make matters even more inscrutable, the timing of death is determined ...
Jan 27, 2016
4
280
Medical research
Optimized gene-editing tool prevents hearing loss in mice with hereditary deafness without detectable off-target effects
Scientists at Harvard Medical School and Boston Children's Hospital have used a novel gene-editing approach to salvage the hearing of mice with genetic hearing loss and succeeded in doing so without any apparent off-target ...
Jul 3, 2019
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0
Medical research
Highly detailed map of the human heart could guide personalized heart treatments
Scientists have created a detailed cellular and molecular map of the healthy human heart to understand how this vital organ functions and to shed light on what goes awry in cardiovascular disease.
Sep 24, 2020
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125
Medical research
Learning from Lassa virus: Researchers discover gene mutations that can result in a congenital disorder
(Medical Xpress)—Researchers have known that two seemingly distant human maladies—a devastating set of hereditary disorders called Walker-Warburg syndrome and infection with the virus that causes hemorrhagic Lassa fever—both ...
Mar 22, 2013
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0
Genetics
Genetic mutation implicated in 'broken' heart
For decades, researchers have sought a genetic explanation for idiopathic dilated cardiomyopathy (DCM), a weakening and enlargement of the heart that puts an estimated 1.6 million Americans at risk of heart failure each year. ...
Feb 15, 2012
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0
Health informatics
New software screens billions of compounds in search of new medicines
As many as 90 percent of promising drug candidates fail before or during human clinical trials, falling into the so-called "valley of death."
Mar 16, 2020
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