Helmholtz Association of German Research Centres
How individuality develops? Experience leads to the growth of new brain cells
How do organisms evolve into individuals that are distinguished from others by their own personal brain structure and behavior? Scientists in Dresden, Berlin, Münster, and Saarbrücken have now taken a decisive step towards ...
Neuroscience
May 09, 2013 |
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Solving puzzle of B-cell lymphoma development
Germinal centers are sites in the organs of the lymphatic system, formed during the course of an immune response to infection, where B cells intensely proliferate and modify their DNA in order to produce ...
Immunology
Sep 23, 2012 |
4.9 / 5 (7) |
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Scientists find Achilles' heel of cancer cells
Several substances inhibiting so-called HDAC enzymes have been studied in trials searching for new anti-cancer drugs in recent years. "Trials have shown that HDAC inhibitors are very effective in arresting growth of cultured ...
Cancer
Nov 05, 2012 |
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Alternate ending -- living on without telomerase
Scientists of the German Cancer Research Center have discovered an alternative mechanism for the extension of the telomere repeat sequence by DNA repair enzymes.
Medical research
Nov 03, 2011 |
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Molecular knock-out alleviates Alzheimer's symptoms in mice
Researchers at the German Center for Neurodegenerative Diseases (DZNE) and the University Medical Center Göttingen (UMG) have identified an enzyme as a possible target for the treatment of Alzheimer's disease. The protein ...
Alzheimer's disease & dementia
Nov 30, 2012 |
5 / 5 (4) |
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Serotonin mediates exercise-induced generation of new neurons
Mice that exercise in running wheels exhibit increased neurogenesis in the brain. Crucial to this process is serotonin signaling. These are the findings of a study by researchers at the Max Delbrück Center ...
Neuroscience
May 13, 2013 |
4.8 / 5 (4) |
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A natural dye obtained from lichens may combat Alzheimer's disease
A red dye derived from lichens that has been used for centuries to color fabrics and food appears to reduce the abundance of small toxic protein aggregates in Alzheimer's disease. The dye, a compound called orcein, and a ...
Medical research
Dec 02, 2011 |
5 / 5 (3) |
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Death cap mushroom poison to arrest pancreatic cancer in mice
The mere thought of an identification error sends a chill down the spine of any mushroom lover: The death cap mushroom (Amanita phalloides), which resembles the common white button mushroom, contains one of the most deadly ...
Cancer
Apr 02, 2012 |
5 / 5 (3) |
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Metastasis stem cells in the blood of breast cancer patients discovered
Individual cancer cells that break away from the original tumor and circulate through the blood stream are considered responsible for the development of metastases. These dreaded secondary tumors are the ...
Cancer
Apr 22, 2013 |
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Evolution in the antibody factory: How immune cells are able to advance their own evolution
Immune system B cells play a crucial role in the defence of pathogens; when they detect such an intruder, they produce antibodies that help to combat the enemy. They concurrently and continuously improve ...
Immunology
Mar 11, 2013 |
4.7 / 5 (3) |
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Misplaced molecules: New insights into the causes of dementia
A team of German and Belgian researchers has succeeded in gaining new insights into the causes of certain movement disorders and forms of dementia. Scientists including Bettina Schmid and Christian Haass from the German Center ...
Neuroscience
Mar 01, 2013 |
3.7 / 5 (3) |
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Tapeworm drug inhibits colon cancer metastasis
A compound that for about 60 years has been used as a drug against tapeworm infection is also apparently effective against colon cancer metastasis, as studies using mice have now shown. The compound silences a gene that triggers ...
Cancer
Jun 17, 2011 |
5 / 5 (2) |
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In the pursuit of dangerous clumps
When normal proteins form protein clumps in the body, then alarm bells start ringing. Such clumps, called "amyloids," are closely associated with Alzheimer's disease and type 2 diabetes, formerly called adult-onset ...
Medical research
Jul 28, 2011 |
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Skin and immune system influence salt storage and regulate blood pressure
High blood pressure is responsible for many cardiovascular diseases that are the leading cause of death in industrialized countries. High salt intake has long been considered a risk factor, but not every type of high blood ...
Medical research
Sep 08, 2012 |
5 / 5 (2) |
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Researchers find controlling element of Huntington's disease
A three molecule complex may be a target for treating Huntington's disease, a genetic disorder affecting the brain. This finding by an international research team including scientists from the German Center for Neurodegenerative ...
Diseases, Conditions, Syndromes
Feb 26, 2013 |
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