Institute for Quality and Efficiency in Health Care

The Institute for Quality and Efficiency in Healthcare (IQWiG) (German: Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesenis) is a German agency responsible for assessing the quality and efficiency of medical treatments, including drugs, non-drug interventions (e.g. surgical procedures), diagnostic and screening methods, and treatment and disease management. IQWiG also supplies health information to patients and the general community. The organization is independent of the pharmaceuticals industry, contracted solely by the Federal Ministry of Health and the Joint Federal Committee. IQWiG was founded in 2004 under the directorship of Dr Peter Sawicki, who was in September 2010 replaced by Dr Jürgen Windeler. Its deputy director is Dr Stefan Lange. IQWiG is divided into the following departments, which publish reports: General health information, written in plain language, is additionally produced by a Health Information department. These departments are also supported by Administration and Communication departments.

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Dabrafenib: Also no added benefit over vemurafenib

Dabrafenib (trade name: Tafinlar) has been approved since August 2013 for the treatment of advanced melanoma. In January 2014, in an early benefit assessment pursuant to the "Act on the Reform of the Market for Medicinal ...

Apr 09, 2014
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Afatinib: Added benefit depends on mutation status

Afatinib (trade name: GIOTRIF) has been approved in Germany since September 2013 for the treatment of adult patients with locally advanced or metastatic non-small cell lung cancer (NSCLC) with activating EGF receptor mutations ...

Feb 19, 2014
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Regorafenib: Hint of minor added benefit

Regorafenib (trade name: Stivarga) has been approved in Germany since August 2013 for adults with metastatic colorectal cancer in whom previous treatments are no longer effective or for whom these alternatives are not an ...

Jan 10, 2014
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COPD: DMP is largely consistent with guidelines

On 3 January 2014 the German Institute for Quality and Efficiency in Health Care (IQWiG) published the results of a literature search for evidence-based clinical practice guidelines on the treatment of people with chronic ...

Jan 08, 2014
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Dabrafenib in melanoma: Added benefit not proven

Dabrafenib (trade name: Tafinlar) has been approved in Germany since August 2013 for the treatment of advanced melanoma.In an early benefit assessment pursuant to the Act on the Reform of the Market for Medicinal Products ...

Jan 07, 2014
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Aflibercept in macular oedema: Added benefit not proven

For the third time in one year, the German Institute for Quality and Efficiency in Health Care (IQWiG) dealt with the drug aflibercept. In an early benefit assessment pursuant to the Act on the Reform of the Market for Medicinal ...

Jan 07, 2014
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Vemurafenib: Result unchanged despite new data

Pursuant to the Act on the Reform of the Market for Medicinal Products (AMNOG), the German Institute for Quality and Efficiency in Health Care (IQWiG) reassessed vemurafenib (trade name: Zelboraf), a drug for the treatment ...

Dec 18, 2013
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Enzalutamide in prostate cancer: Hints of added benefit

Enzalutamide (trade name: Xtandi) has been approved since June 2013 for men with metastatic prostate cancer in whom the commonly used hormone blockade is no longer effective and who have already been treated with the cytostatic ...

Dec 06, 2013
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