Cancer driver genes are those with mutations that are essential for tumor development and spread. Led by ICREA researcher Patrick Aloy, scientists from the Structural Bioinformatics and Network Biology (SBNB) Laboratory at ...
Sep 22, 2020
0
4
Living implies change. This is what happens to the cells of our bodies as we grow older: They accumulate genetic alterations, most of which are harmless. However, in some specific cases, these mutations can affect certain ...
Nov 18, 2019
1
43
This is the first time that a method allows scientists to monitor aggregation while simultaneously detect a structural pattern responsible for the toxicity of beta-amyloid aggregation.The researchers state that these studies ...
Oct 1, 2014
0
0
Fibrosis is associated with various chronic and life-threatening conditions, including pulmonary fibrosis, liver cirrhosis, kidney disease, and cardiovascular diseases, among others. These conditions collectively contribute ...
Dec 14, 2023
0
32
Scientific Reports, a Nature group journal, has recently published results that challenge the findings of studies to date on the initial aggregates formed by amyloid beta, a protein closely associated with the onset and development ...
Oct 14, 2015
0
12
(Phys.org)—Researchers headed by Maria Macias an ICREA researcher at the Institute for Research in Biomedicine (IRB Barcelona) and Joan Massagué, a Howard Hughes Medical Institute investigator at Memorial Sloan-Kettering ...
Aug 24, 2012
0
0
Transcription factors play essential roles in turning the genetic information encoded in genes into proteins in all cells and organisms. These regulatory proteins bind DNA, turn genes on or off, and control the rate at which ...
Dec 4, 2023
0
15
The Biomedical Genomics laboratory at IRB Barcelona has developed a computational tool that identifies cancer driver mutations for each tumor type.
Jul 29, 2021
0
159
A study led by scientists at the Institute for Research in Biomedicine (IRB Barcelona) and published in Nature Communications proposes chaperone protein Hps70 as an attractive therapeutic target for the treatment of Kennedy's ...
Aug 8, 2019
0
15
About 40-50% of all colorectal patients relapse in the form of metastasis. In the last three years, several molecular classifications have been proposed to identify colorectal cancer patients at risk of relapse. Today in ...
Feb 23, 2015
0
24
