Cancer treatments, including chemotherapy, in addition to killing a large number of tumor cells, also result in the generation of senescent tumor cells (also called "zombie cells"). While senescent cells do not reproduce, ...
Jan 24, 2024
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Scientists at the Institute for Research in Biomedicine (IRB Barcelona), headed by Jens Lüders, group leader of the Microtubule Organization Laboratory, have described a new molecular mechanism that plays a key role in forming ...
Jul 22, 2016
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Two complementary research articles, published simultaneously in the journals Science and Cell Stem Cell by a team of scientists from the UPF and IRB Barcelona, reveal that central and peripheral circadian clocks coordinate ...
May 2, 2024
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Physicians currently have no tools to help them detect breast cancer patients who will suffer metastasis, a process that occurs in 15 to 20 percent of cases. In particular, they are unable to identify those patients that ...
Oct 20, 2017
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Senescent cells are damaged cells that no longer perform their normal roles, but are not dead—hence, they are commonly known as "zombie cells." These cells interfere with the functioning of the tissue in which they accumulate. ...
Jul 27, 2018
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Breast cancer is the most common form of cancer among women, with more than 2 million new cases diagnosed each year. In cases where the tumor remains localized in the breast, survival rates are remarkably high, at around ...
Nov 9, 2023
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Cancer cells are characterised by the ability to evade apoptosis, a type of programmed cell death that allows the organism to remove damaged cells. Many studies devoted to new chemotherapy treatments aim to induce apoptosis ...
Apr 17, 2019
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In 2007, in an article published in Nature Neuroscience, scientists at the Institute for Research in Biomedicine (IRB Barcelona) headed by Joan Guinovart, an authority on glycogen metabolism, reported that in Lafora Disease ...
Feb 27, 2014
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To understand the molecular bases of cancer, it is imperative to determine the genetic alterations responsible for the development and spread of this condition and to identify the mechanisms through which healthy cells become ...
Dec 2, 2019
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The Translational Control of Cell Cycle and Differentiation Lab at IRB Barcelona, led by ICREA researcher Raúl Méndez, has published a study in the journal Science Advances that has identified a key factor in the development ...
May 18, 2020
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