Journal of the National Cancer Institute

Oncology & Cancer

Colorectal cancer gene database helpful in furthering research

The CRCgene database, which gathers all genetic association studies on colorectal cancer, allows for researchers to accurately interpret the risk factors of the disease and provides insight into the direction of further colorectal ...

Oncology & Cancer

Plant-based compound slows breast cancer in a mouse model

The natural plant compound phenethyl isothiocyanate (PEITC) hinders the development of mammary tumors in a mouse model with similarities to human breast cancer progression, according to a study published August 2 in the Journal ...

Oncology & Cancer

Vitamin E may lower liver cancer risk

High consumption of vitamin E either from diet or vitamin supplements may lower the risk of liver cancer, according to a study published July 17 in the Journal of the National Cancer Institute.

Oncology & Cancer

Fertility drug usage and cancer risk

Women using fertility drugs who did not conceive a 10-plus week pregnancy were at a statistically significant reduced risk of breast cancer compared to nonusers; however, women using the drugs who conceived a 10-plus week ...

Oncology & Cancer

Probing the mechanism of ADAM28-mediated cancer metastasis

ADAM28, a metalloproteinase belonging to the ADAM gene family, cleaves the von Willebrand factor (VWF) and inhibits VWF-mediated cancer cell apoptosis, thereby enhancing lung metastases, so inhibiting its expression gives ...

Oncology & Cancer

Early-life risk factors for non-Hodgkin lymphoma

Factors influencing early life non-Hodgkin lymphoma (NHL) incidence include family characteristics, high fetal growth, older maternal age, low birth order, and male gender, according to a study published May 22 in the Journal ...

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