Public Library of Science

Pre-clinical animal research must improve

Less than five percent of promising basic science discoveries that claim clinical relevance lead to approved drugs within a decade, partly because of flawed pre-clinical animal research. A number of recent initiatives seek ...

Jul 23, 2013
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Bias pervades the scientific reporting of animal studies

A new study published in the open access journal PLOS Biology suggests that the scientific literature could be compromised by substantial bias in the reporting of animal studies, and may be giving a misleading picture of the ...

Jul 17, 2013
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