Public Library of Science

Pre-clinical animal research must improve

Less than five percent of promising basic science discoveries that claim clinical relevance lead to approved drugs within a decade, partly because of flawed pre-clinical animal research. A number of recent initiatives seek ...

Jul 23, 2013
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Bias pervades the scientific reporting of animal studies

A new study published in the open access journal PLOS Biology suggests that the scientific literature could be compromised by substantial bias in the reporting of animal studies, and may be giving a misleading picture of the ...

Jul 17, 2013
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Inflammation links social adversity and diabetes

Diabetes is strongly associated with socioeconomic status (SES): low income, low education, and low occupational status are all linked to a higher risk for diabetes. Trying to understand the mechanisms underlying the association, ...

Jul 02, 2013
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