Rockefeller University
Wip1 could be new target for cancer treatment
Researchers have uncovered mutations in the phosphatase Wip1 that enable cancer cells to foil the tumor suppressor p53, according to a study in The Journal of Cell Biology. The results could provide a new ...
Cancer
May 06, 2013 |
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Researchers create map of 'shortcuts' between all human genes
Some diseases are caused by single gene mutations. Current techniques for identifying the disease-causing gene in a patient produce hundreds of potential gene candidates, making it difficult for scientists to pinpoint the ...
Genetics
Mar 18, 2013 |
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Study of fruit fly sleep reveals a genetic basis of insomnia
(Medical Xpress) -- On the surface, it’s simple: when night falls, our bodies get sleepy. But behind the scenes, a series of complex molecular events, controlled by our genes, is hard at work to make ...
Neuroscience
Jan 30, 2012 |
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Potent antibodies neutralize HIV and could offer new therapy, study finds
(Medical Xpress)—Having HIV/AIDS is no longer a death sentence, but it's still a lifelong illness that requires an expensive daily cocktail of drugs—and it means tolerating those drugs' side effects and ...
Immunology
Nov 07, 2012 |
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Mechanism of mutant histone protein in childhood brain cancer revealed
(Medical Xpress)—Most cancer treatments are blunt. In an attempt to eradicate tumors, oncologists often turn to radiation or chemotherapy, which can damage healthy tissue along with the cancerous growths. ...
Cancer
Apr 01, 2013 |
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Protein proves to be vital in immune response to bacteria
(Medical Xpress) -- A team of researchers led by scientists at Rockefeller University have discovered that a protein once thought to be mainly involved in antiviral immunity is in fact more important in ...
Medical research
Aug 13, 2012 |
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Scientists discover gene mutation that causes children to be born without spleen
The spleen is rarely noticed, until it is missing. In children born without this organ, that doesn't happen until they become sick with life-threatening bacterial infections. An international team of researchers led by scientists ...
Genetics
Apr 11, 2013 |
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Collaboration finds kidney disease tied to DNA damage
(Medical Xpress) -- A research collaboration involving Rockefeller University and more than two dozen other institutions has found a link between a gene mutation and chronic kidney failure. The study, published ...
Genetics
Aug 09, 2012 |
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Stay-at-home transcription factor prevents neurodegeneration
A study in The Journal of Cell Biology shows how a transcription factor called STAT3 remains in the axon of nerve cells to help prevent neurodegeneration. The findings could pave the way for future drug therapies to slow ...
Medical research
Oct 29, 2012 |
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Starr collaboration illuminates mysterious pathway to immortality in cancer cells
(Medical Xpress) -- Cancer cells are immortal because they circumvent failsafe mechanisms that stop out-of-control cell proliferation. One of these mechanisms – the progressive shortening of chromosomes ...
Cancer
Jul 25, 2012 |
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Rockefeller scientists pioneer new method to determine mechanisms of drug action
(Medical Xpress) -- Knowing that a drug works is great. Knowing how it works is a luxury. And until now, determining a drug’s mechanism of action has been a tedious and difficult process for scientists.
Medical research
May 25, 2012 |
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Influenza 'histone mimic' suppresses antiviral response
(Medical Xpress) -- For a virus like influenza, the key to success isn't in overpowering the immune system, it’s in tricking it. A team of researchers led by scientists at The Rockefeller University has ...
Medical research
Mar 14, 2012 |
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Sweat glands grown from newly identified stem cells
To date, few fundamentals have been known about the most common gland in the body, the sweat glands that are essential to controlling body temperature, allowing humans to live in the world’s diverse climates. ...
Medical research
Jul 06, 2012 |
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Brain displays an intrinsic mechanism for fighting infection
(Medical Xpress)—White blood cells have long reigned as the heroes of the immune system. When an infection strikes, the cells, produced in bone marrow, race through the blood to fight off the pathogen. ...
Medical research
Nov 19, 2012 |
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First 'live' imaging of specialized immune system cells reveals new clues about body's security system
To keep the body safe, the immune system enlists more than one form of protection. A circulating task force of immune system cells monitors the body’s periphery, and sends information back to field command centers — ...
Medical research
Dec 21, 2011 |
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