Rockefeller University
Researchers create map of 'shortcuts' between all human genes
Some diseases are caused by single gene mutations. Current techniques for identifying the disease-causing gene in a patient produce hundreds of potential gene candidates, making it difficult for scientists to pinpoint the ...
Genetics
Mar 18, 2013 |
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Two-faced leukemia?
One kind of leukemia sometimes masquerades as another, according to a study published online this week in the Journal of Experimental Medicine.
Cancer
Dec 12, 2011 |
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Protein family linked to autism suppresses the development of inhibitory synapses
Synapse development is promoted by a variety of cell adhesion molecules that connect neurons and organize synaptic proteins. Many of these adhesion molecules are linked to neurodevelopmental disorders; mutations ...
Medical research
Jan 28, 2013 |
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Brain displays an intrinsic mechanism for fighting infection
(Medical Xpress)—White blood cells have long reigned as the heroes of the immune system. When an infection strikes, the cells, produced in bone marrow, race through the blood to fight off the pathogen. ...
Medical research
Nov 19, 2012 |
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Scientists use nature against nature to develop an antibiotic with reduced resistance
A new broad range antibiotic, developed jointly by scientists at The Rockefeller University and Astex Pharmaceuticals, has been found to kill a wide range of bacteria, including drug-resistant Staphylococcus (MRSA) bacter ...
Medications
Apr 10, 2013 |
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Starr collaboration illuminates mysterious pathway to immortality in cancer cells
(Medical Xpress) -- Cancer cells are immortal because they circumvent failsafe mechanisms that stop out-of-control cell proliferation. One of these mechanisms – the progressive shortening of chromosomes ...
Cancer
Jul 25, 2012 |
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Scientists create first genetically humanized mouse model for hepatitis C
Scientists at Rockefeller University and The Scripps Research Institute have developed the first genetically humanized mouse model for hepatitis C, an achievement that will enable researchers to test molecules that block ...
Medical research
Jun 08, 2011 |
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Getting down to the heart of the (gray) matter to treat Parkinson's disease
An agent under consideration for use in PET imaging combats neuronal death to relieve Parkinsonian symptoms in animal models, according to a study published on April 2nd in the Journal of Experimental Medicine.
Parkinson's & Movement disorders
Apr 02, 2012 |
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Potent antibodies neutralize HIV and could offer new therapy, study finds
(Medical Xpress)—Having HIV/AIDS is no longer a death sentence, but it's still a lifelong illness that requires an expensive daily cocktail of drugs—and it means tolerating those drugs' side effects and ...
Immunology
Nov 07, 2012 |
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Sweat glands grown from newly identified stem cells
To date, few fundamentals have been known about the most common gland in the body, the sweat glands that are essential to controlling body temperature, allowing humans to live in the world’s diverse climates. ...
Medical research
Jul 06, 2012 |
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Noncoding RNA may promote Alzheimer's disease
Researchers pinpoint a small RNA that spurs cells to manufacture a particular splice variant of a key neuronal protein, potentially promoting Alzheimer's disease (AD) or other types of neurodegeneration. The ...
Medical research
May 30, 2011 |
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Decoding chronic lymphocytic leukemia
A paper published online on June 13 in the Journal of Experimental Medicine identifies new gene mutations in patients with chronic lymphocytic leukemia (CLL) -- a disease often associated with lack of response to chemotherapy and po ...
Cancer
Jun 13, 2011 |
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New perspectives on sensory mechanisms
The latest Perspectives in General Physiology series examines the mechanisms of visual, aural, olfactory, and tactile processes that inform us about the environment. The series appears in the September 2011 ...
Medical research
Aug 29, 2011 |
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Bacteria enter via mucus-making gut cells
Cells making slippery mucus provide a sticking point for disease-causing bacteria in the gut, according to a study published on October 3 in the Journal of Experimental Medicine.
Diseases, Conditions, Syndromes
Oct 03, 2011 |
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Simple, model-free analysis of voltage-gated channels
A new study in the Journal of General Physiology provides fresh insight into voltage-gated channels—transmembrane ion channels that play a critical role in the function of neuronal and muscle tissue.
Medical research
Dec 12, 2011 |
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