Thomas Jefferson University

Medical research

New role for death molecule

Cellular death is vital for health. Without it, we could develop autoimmune diseases or cancers. But a cell's decision to self-destruct is tightly regulated, so that it only happens to serve the best interests of the body. ...

Medical research

Rock-a-bye fly: Why vibrations lead to sleepiness

It is common practice to rock babies to sleep. Children and grownups also get drowsy during long car rides. There is something about gentle mechanical stimuli that makes humans of all ages sleepy. Sleep in fruit flies is ...

Oncology & Cancer

How melanoma evades targeted therapies

Melanoma is the leading cause of death from skin cancer. Many patients develop metastatic disease that spreads to other parts of the body. One commonly used targeted therapy for metastatic melanomas works by attacking melanomas ...

Medications

Statins may lower mortality in high-risk prostate cancer patients

Among high-risk prostate cancer patients—those with high PSA and Gleason scores of 8 or more—many will develop a difficult-to-treat disease. Preliminary research suggests that two commonly prescribed medications, cholesterol-lowering ...

Oncology & Cancer

Lynchpin molecule for the spread of cancer found

Cancer is a disease of cell growth, but most tumors only become lethal once they metastasize or spread from their first location to sites throughout the body. For the first time, researchers at Thomas Jefferson University ...

Oncology & Cancer

For prostate cancer, more radiation may not improve survival

New technology has enabled doctors to administer higher doses of radiation to prostate cancer patients with fewer side effects. However, a new study shows that escalating the dose may not actually help a patient in the long ...

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