Diseases, Conditions, Syndromes

TB discovery paves the way for drugs that prevent lung destruction

Scientists have identified a key enzyme responsible for destroying lung tissue in tuberculosis (TB), they report today in the Journal of Clinical Investigation. Drugs that inhibit this enzyme are already available, meaning ...

Obstetrics & gynaecology

Maternal antibiotic treatment may harm preemies' lungs

New research in mice suggests that exposure to antibiotics before birth may impair lung development in premature infants. The study, the first to explore the gut-lung axis in prematurity, is published ahead of print in the ...

Diseases, Conditions, Syndromes

Human microbiome influences rotavirus vaccine response

In a proof-of-concept study in healthy adult men, scientists in the Netherlands found that microbiome manipulation with antibiotics influenced the response to oral rotavirus vaccine. Specifically, they found higher levels ...

Diseases, Conditions, Syndromes

Premature babies harbor fewer, but more dangerous microbe types

One of the most comprehensive studies to date of the microbes that are found in extremely low-birthweight infants found that hard-to-treat Candida fungus is often present, as well as some harmful bacteria and parasites.

Medications

Benefits, risks seen with antibiotics-first for appendicitis

Antibiotics may be a good choice for some, but not all, patients with appendicitis, according to results from the Comparing Outcomes of antibiotic Drugs and Appendectomy (CODA) Trial reported today in the New England Journal ...

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