Exploring why some newborns develop severe infections
Compared to adults, newborns are highly susceptible to infections and these infections can cause serious health complications and even death.
Mar 15, 2024
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Compared to adults, newborns are highly susceptible to infections and these infections can cause serious health complications and even death.
Mar 15, 2024
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A person's age, sex and location are correlated with the chance that they have a bloodstream infection that is resistant to antibiotics, according to a new study published in PLOS Medicine by Gwenan Knight of the London School ...
Mar 14, 2024
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A new collaborative study discloses the discovery and application of a new therapeutic strategy to target the multidrug-resistant bacterium Salmonella enterica in vivo, with promising results. The results were published in ...
Mar 7, 2024
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Degenerative arthritis is no longer exclusive to the elderly population. According to the National Health Insurance Service report covering the years from 2012 to 2022, there has been a 22.8% increase in the prevalence of ...
Mar 5, 2024
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Certain medications for multiple sclerosis (MS) called monoclonal antibodies, taken while breastfeeding, may not affect the development of a child during the first three years of life, according to a preliminary study presenting ...
Mar 4, 2024
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Children whose mothers have received antibiotic treatment during childbirth are more likely to develop autoimmune diseases compared to their counterparts, according to a recent registry-based study published in the American ...
Feb 22, 2024
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Dealing with chronic urinary tract infections (UTIs) means facing more than the occasional discomfort. It's like being on a never ending battlefield against an unseen adversary, making simple daily activities a trial.
Feb 21, 2024
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A new study describes the use of phage therapy to eradicate multi-drug resistant Pseudomonas aeruginosa infections in a living organism (in vivo) with important new implications for antibiotic resistance.
Feb 21, 2024
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In the first comprehensive evidence-based guideline on the use of fecal microbiota-based therapies for gastrointestinal disease, the American Gastroenterological Association recommends fecal microbiota transplant (FMT) for ...
Feb 21, 2024
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Across the European continent, sexually transmitted infections (STI) caused by Neisseria gonorrhoeae have gone up in recent years, according to data from the European Centre for Disease Prevention and Control. New data from ...
Feb 20, 2024
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In common usage, an antibiotic (from the Ancient Greek: ἀντί – anti, "against", and βίος – bios, "life") is a substance or compound that kills bacteria or inhibits their growth. Antibiotics belong to the broader group of antimicrobial compounds, used to treat infections caused by microorganisms, including fungi and protozoa.
The term "antibiotic" was coined by Selman Waksman in 1942 to describe any substance produced by a microorganism that is antagonistic to the growth of other microorganisms in high dilution. This original definition excluded naturally occurring substances that kill bacteria but are not produced by microorganisms (such as gastric juice and hydrogen peroxide) and also excluded synthetic antibacterial compounds such as the sulfonamides. Many antibiotics are relatively small molecules with a molecular weight less than 2000 Da.[citations needed]
With advances in medicinal chemistry, most antibiotics are now semisynthetic—modified chemically from original compounds found in nature, as is the case with beta-lactams (which include the penicillins, produced by fungi in the genus Penicillium, the cephalosporins, and the carbapenems). Some antibiotics are still produced and isolated from living organisms, such as the aminoglycosides, and others have been created through purely synthetic means: the sulfonamides, the quinolones, and the oxazolidinones. In addition to this origin-based classification into natural, semisynthetic, and synthetic, antibiotics may be divided into two broad groups according to their effect on microorganisms: those that kill bacteria are bactericidal agents, while those that only impair bacterial growth are known as bacteriostatic agents.
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